U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Sat Dec 16 13:26:33 GMT 2023
Edited
by admin
on Sat Dec 16 13:26:33 GMT 2023
Nucleic Acid Subtype
Sequence Type COMPLETE
Record UNII
3N4G7RE66Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
APATORSEN SODIUM
USAN   WHO-DD  
USAN  
Official Name English
APATORSEN SODIUM [USAN]
Common Name English
OGX-427
Code English
Apatorsen sodium [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1291
Created by admin on Sat Dec 16 13:26:33 GMT 2023 , Edited by admin on Sat Dec 16 13:26:33 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C142928
Created by admin on Sat Dec 16 13:26:33 GMT 2023 , Edited by admin on Sat Dec 16 13:26:33 GMT 2023
PRIMARY
USAN
AB-39
Created by admin on Sat Dec 16 13:26:33 GMT 2023 , Edited by admin on Sat Dec 16 13:26:33 GMT 2023
PRIMARY
EVMPD
SUB75707
Created by admin on Sat Dec 16 13:26:33 GMT 2023 , Edited by admin on Sat Dec 16 13:26:33 GMT 2023
PRIMARY
ChEMBL
CHEMBL3039553
Created by admin on Sat Dec 16 13:26:33 GMT 2023 , Edited by admin on Sat Dec 16 13:26:33 GMT 2023
PRIMARY
FDA UNII
3N4G7RE66Y
Created by admin on Sat Dec 16 13:26:33 GMT 2023 , Edited by admin on Sat Dec 16 13:26:33 GMT 2023
PRIMARY
DRUG BANK
DBSALT002489
Created by admin on Sat Dec 16 13:26:33 GMT 2023 , Edited by admin on Sat Dec 16 13:26:33 GMT 2023
PRIMARY
PUBCHEM
91865087
Created by admin on Sat Dec 16 13:26:33 GMT 2023 , Edited by admin on Sat Dec 16 13:26:33 GMT 2023
PRIMARY
CAS
915443-09-3
Created by admin on Sat Dec 16 13:26:33 GMT 2023 , Edited by admin on Sat Dec 16 13:26:33 GMT 2023
PRIMARY
Sugar Site Range Site Count
Deoxyribose (DNA) 1_5-1_16 12 / 20
2'-O-Methyl-Ribose 1_1-1_4;1_17-1_20 8 / 20
Linkage Site Range Site Count
Sodium Phosporothioate 1_2-1_20 19 / 19
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
NUCLEOSIDE_SUBSTITUTION [1_5] [1_7] [1_10] [1_12] [1_14] SITE_SPECIFIC 5-METHYLDEOXYCYTIDINE B200GV71QM
NUCLEOSIDE_SUBSTITUTION [1_17] [1_20] 2'-O-(2-METHOXYETHYL)-5-METHYLURIDINE 9Q36I4D9VB