EFPEGLENATIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:51:22 GMT 2025` Edited by `admin` on `Mon Mar 31 21:51:22 GMT 2025`
Protein Type	FC FUSION PROTEIN
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	3M1V5Z2270
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

HM-11260C

Preferred Name

English

EFPEGLENATIDE

Official Name

English

efpeglenatide [INN]

Common Name

English

SAR-439977

Code

English

EFPEGLENATIDE [USAN]

Common Name

English

HM11260C

Code

English

SAR439977

Code

English

POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-HYDRO-.OMEGA.-HYDROXY-, 26-ETHER WITH N-(2-(1H-IMIDAZOL-5-YL)ACETYL)GLYCYL-L-.ALPHA.-GLUTAMYLGLYCYL-L-THREONYL-L-PHENYLALANYL-L-THREONYL-L-SERYL-L-.ALPHA.-ASPARTYL-L-LEUCYL-L-SERYL-L-LYSYL-L-GLUTAMINYL-L-METHIONYL-L-.ALP

Common Name

English

LANGLENATIDE

Common Name

English

EXENATIDE DERIVATIVE AND HUMAN IGG4 FC DIMER LINKED TOGETHER WITH POLYETHYLENE GLYCOL DERIVATIVE: N 6.27 , N . 1'-(.OMEGA.-(OXYPROPANE-1,3-DIYL)-.ALPHA.-(PROPANE-1,3-DIYL)POLY(OXYETHYLENE)) (1-(IMIDAZOL-4-YLACETIC ACID))EXENDIN-4 HELODERMA SUSPECTUM (GIL

Systematic Name

English

IMIDAZOACETYL-EXENDIN-4-PEG-IMMUNOGLOBULIN FC FRAGMENT CONJUGATE

Common Name

English

Efpeglenatide [WHO-DD]

Common Name

English

Code System Code Type Description

CAS

1454680-59-1

Created by admin on Mon Mar 31 21:51:22 GMT 2025 , Edited by admin on Mon Mar 31 21:51:22 GMT 2025

ALTERNATIVE

CAS

1296200-77-5

Created by admin on Mon Mar 31 21:51:22 GMT 2025 , Edited by admin on Mon Mar 31 21:51:22 GMT 2025

PRIMARY

DRUG BANK

DB15650

Created by admin on Mon Mar 31 21:51:22 GMT 2025 , Edited by admin on Mon Mar 31 21:51:22 GMT 2025

PRIMARY

USAN

HI-196

Created by admin on Mon Mar 31 21:51:22 GMT 2025 , Edited by admin on Mon Mar 31 21:51:22 GMT 2025

PRIMARY

INN

9580

Created by admin on Mon Mar 31 21:51:22 GMT 2025 , Edited by admin on Mon Mar 31 21:51:22 GMT 2025

PRIMARY

SMS_ID

100000180105

Created by admin on Mon Mar 31 21:51:22 GMT 2025 , Edited by admin on Mon Mar 31 21:51:22 GMT 2025

PRIMARY

FDA UNII

3M1V5Z2270

Created by admin on Mon Mar 31 21:51:22 GMT 2025 , Edited by admin on Mon Mar 31 21:51:22 GMT 2025

PRIMARY

NCI_THESAURUS

C166682

Created by admin on Mon Mar 31 21:51:22 GMT 2025 , Edited by admin on Mon Mar 31 21:51:22 GMT 2025

PRIMARY

From	To
1_3	2_3
1_35	1_95
1_141	1_199
2_35	2_95
2_141	2_199

Related Record Type Details


					EF38T7N5MI

GLUCAGON-LIKE PEPTIDE 1 RECEPTOR

TARGET -> AGONIST

Amount:

Related Record Type Details


					3M1V5Z2270

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[3_1]		His		IMIDAZOLEACETIC ACID	IGZ30Z24EJ
AMINO ACID SUBSTITUTION	[3_39]		Ser		SERINAMIDE	CIJ0MD19SE
AMINO ACID SUBSTITUTION	[1_1]		Pro		LYSYL-PEG-PROLYL LINKER	C8170Q4JSX
AMINO ACID SUBSTITUTION	[3_27]		Lys		LYSYL-PEG-PROLYL LINKER	C8170Q4JSX

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL