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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H38O2
Molecular Weight 346.5466
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ROSTEROLONE

SMILES

[H][C@@]12CC[C@@](O)(CCC)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])CC[C@@]4([H])CC(=O)C[C@H](C)[C@]34C

InChI

InChIKey=IMFNBOMNWHWKQD-MXENSADDSA-N
InChI=1S/C23H38O2/c1-5-10-23(25)12-9-19-18-7-6-16-14-17(24)13-15(2)22(16,4)20(18)8-11-21(19,23)3/h15-16,18-20,25H,5-14H2,1-4H3/t15-,16-,18-,19-,20-,21-,22-,23-/m0/s1

HIDE SMILES / InChI

Molecular Formula C23H38O2
Molecular Weight 346.5466
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 8 / 8
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Rosterolone (also known as a17α-propylmesterolone) is a synthetic 5alpha-reduced steroid that was studied for acne treatment on animal models. It was shown that the topical administration was more effective than systemic treatment. Rosterolone exerted a potent topical sebosuppressive effect in the animal model. This compound has never been marketed.

Approval Year

Substance Class Chemical
Record UNII
3L5C5C8ZNG
Record Status Validated (UNII)
Record Version