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Details

Stereochemistry ACHIRAL
Molecular Formula C19H14F3NO
Molecular Weight 329.3158
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLURIDONE

SMILES

CN1C=C(C2=CC=CC=C2)C(=O)C(=C1)C3=CC=CC(=C3)C(F)(F)F

InChI

InChIKey=YWBVHLJPRPCRSD-UHFFFAOYSA-N
InChI=1S/C19H14F3NO/c1-23-11-16(13-6-3-2-4-7-13)18(24)17(12-23)14-8-5-9-15(10-14)19(20,21)22/h2-12H,1H3

HIDE SMILES / InChI

Molecular Formula C19H14F3NO
Molecular Weight 329.3158
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Fluridone, an herbicide that used for controlling invasive aquatic plants such as hydrilla in surface water bodies. It inhibits carotenoid synthesis in targeted plant species, preventing photosynthesis and ultimately causing mortality. This compound contains a 4(1H)-pyridone and a trifluoromethyl-benzene moiety, which are also present in molecules with analgesic and anti-inflammatory properties. Experiments on rodents have confirmed that fluridone could represent a new prototype of an anti-inflammatory drug.

Approval Year

PubMed

PubMed

TitleDatePubMed
Fluridone as a new anti-inflammatory drug.
2013-11-15
Carotenoid inhibitors reduce strigolactone production and Striga hermonthica infection in rice.
2010-12-01
Fluridone affects quiescent centre division in the Arabidopsis thaliana root stem cell niche.
2010-12
ABA promotes quiescence of the quiescent centre and suppresses stem cell differentiation in the Arabidopsis primary root meristem.
2010-12
Initial characterisation of low and high seed dormancy populations of Lolium rigidum produced by repeated selection.
2010-10-15
Endogenous abscisic acid as a key switch for natural variation in flooding-induced shoot elongation.
2010-10
The plant-specific SR45 protein negatively regulates glucose and ABA signaling during early seedling development in Arabidopsis.
2010-10
Abscisic acid in salt stress predisposition to phytophthora root and crown rot in tomato and chrysanthemum.
2010-09
Arabidopsis RING E3 ligase XBAT32 regulates lateral root production through its role in ethylene biosynthesis.
2010-08
A new lead chemical for strigolactone biosynthesis inhibitors.
2010-07
A genetic locus and gene expression patterns associated with the priming effect on lettuce seed germination at elevated temperatures.
2010-05
Nitric oxide mediates the hormonal control of Crassulacean acid metabolism expression in young pineapple plants.
2010-04
Storage behavior and changes in concentrations of abscisic acid and gibberellins during dormancy break and germination in seeds of Phellodendron amurense var. wilsonii (Rutaceae).
2010-02
Fungal endophytes-induced abscisic acid is required for flavonoid accumulation in suspension cells of Ginkgo biloba.
2010-02
Abscisic acid has contrasting effects on salt excretion and polyamine concentrations of an inland and a coastal population of the Mediterranean xero-halophyte species Atriplex halimus.
2009-10
Identification and characterization of bZIP-type transcription factors involved in carrot (Daucus carota L.) somatic embryogenesis.
2009-10
Cloning and functional analysis of 9-cis-epoxycarotenoid dioxygenase (NCED) genes encoding a key enzyme during abscisic acid biosynthesis from peach and grape fruits.
2009-08-15
ABA, GA(3), and nitrate may control seed germination of Crithmum maritimum (Apiaceae) under saline conditions.
2009-08
Relationship between the degree of carotenoid depletion and function of the photosynthetic apparatus.
2009-07-17
Abscisic acid negatively regulates elicitor-induced synthesis of capsidiol in wild tobacco.
2009-07
ABA inhibits germination but not dormancy release in mature imbibed seeds of Lolium rigidum Gaud.
2009
The role of ABA in triggering ethylene biosynthesis and ripening of tomato fruit.
2009
Involvement of ABA in induction of secondary dormancy in barley (Hordeum vulgare L.) seeds.
2008-12
Genetic variation for lettuce seed thermoinhibition is associated with temperature-sensitive expression of abscisic Acid, gibberellin, and ethylene biosynthesis, metabolism, and response genes.
2008-10
Assessment of potential aquatic herbicide impacts to California aquatic ecosystems.
2008-10
Roles of gibberellins and abscisic acid in dormancy and germination of red bayberry (Myrica rubra) seeds.
2008-09
Abscisic acid accumulation in the roots of nutrient-limited plants: its impact on the differential growth of roots and shoots.
2008-08-25
Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient.
2008-06-18
Mutations of genes in synthesis of the carotenoid precursors of ABA lead to pre-harvest sprouting and photo-oxidation in rice.
2008-04
The ABA1 gene and carotenoid biosynthesis are required for late skotomorphogenic growth in Arabidopsis thaliana.
2008-02
Abscisic acid controls calcium-dependent egress and development in Toxoplasma gondii.
2008-01-10
Regulatory involvement of abscisic acid in potato tuber wound-healing.
2008
Tomato strigolactones are derived from carotenoids and their biosynthesis is promoted by phosphate starvation.
2008
Abscisic acid regulates TSRF1-mediated resistance to Ralstonia solanacearum by modifying the expression of GCC box-containing genes in tobacco.
2008
Cell division versus cell elongation: the control of radicle elongation during thermoinhibition of Tagetes minuta achenes.
2007-12
[Study on conditions of seed germination of Cistanche].
2007-09
Ethylene insensitivity results in down-regulation of rubisco expression and photosynthetic capacity in tobacco.
2007-07
Gene expression pattern at desiccation in the anther of Lilium longiflorum.
2007-07
Strigolactones: promising plant signals.
2007-05
Dissecting the biosynthetic pathway for the bypass1 root-derived signal.
2007-02
Expression of ASCORBATE PEROXIDASE 8 in roots of rice (Oryza sativa L.) seedlings in response to NaCl.
2007
On the role of abscisic acid in seed dormancy of red rice.
2007
Dynamic analysis of ABA accumulation in relation to the rate of ABA catabolism in maize tissues under water deficit.
2007
Gene expression profiles of Arabidopsis Cvi seeds during dormancy cycling indicate a common underlying dormancy control mechanism.
2006-06
Aquatic herbicides and herbicide contaminants: In vitro cytotoxicity and cell-cycle analysis.
2006-06
Physiological changes in gentian axillary buds during two-step preculturing with sucrose that conferred high levels of tolerance to desiccation and cryopreservation.
2006-06
Expression of PsGRP1, a novel glycine rich protein gene of Pisum sativum, is induced in developing fruit and seed and by ABA in pistil and root.
2006-05
Characterization of a higher plant herbicide-resistant phytoene desaturase and its use as a selectable marker.
2006-03
The regulator of G-protein signaling proteins involved in sugar and abscisic acid signaling in Arabidopsis seed germination.
2006-01
Post-anthesis development of inferior and superior spikelets in rice in relation to abscisic acid and ethylene.
2006
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:01:06 GMT 2025
Edited
by admin
on Mon Mar 31 19:01:06 GMT 2025
Record UNII
3L0JQA61JX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AVAST
Preferred Name English
FLURIDONE
HSDB   ISO  
Common Name English
1-METHYL-3-PHENYL-5-(.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)-4-PYRIDONE
Systematic Name English
PRIDE
Brand Name English
FLURIDONE [ISO]
Common Name English
1-METHYL-3-PHENYL-5-(3-(TRIFLUOROMETHYL)PHENYL)-4(1H)-PYRIDINONE
Systematic Name English
EL-171
Code English
FLURIDONE [HSDB]
Common Name English
SONAR
Brand Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 112900
Created by admin on Mon Mar 31 19:01:06 GMT 2025 , Edited by admin on Mon Mar 31 19:01:06 GMT 2025
Code System Code Type Description
HSDB
6653
Created by admin on Mon Mar 31 19:01:06 GMT 2025 , Edited by admin on Mon Mar 31 19:01:06 GMT 2025
PRIMARY
EPA CompTox
DTXSID8024107
Created by admin on Mon Mar 31 19:01:06 GMT 2025 , Edited by admin on Mon Mar 31 19:01:06 GMT 2025
PRIMARY
CAS
59756-60-4
Created by admin on Mon Mar 31 19:01:06 GMT 2025 , Edited by admin on Mon Mar 31 19:01:06 GMT 2025
PRIMARY
FDA UNII
3L0JQA61JX
Created by admin on Mon Mar 31 19:01:06 GMT 2025 , Edited by admin on Mon Mar 31 19:01:06 GMT 2025
PRIMARY
PUBCHEM
43079
Created by admin on Mon Mar 31 19:01:06 GMT 2025 , Edited by admin on Mon Mar 31 19:01:06 GMT 2025
PRIMARY
WIKIPEDIA
Fluridone
Created by admin on Mon Mar 31 19:01:06 GMT 2025 , Edited by admin on Mon Mar 31 19:01:06 GMT 2025
PRIMARY
ECHA (EC/EINECS)
261-916-6
Created by admin on Mon Mar 31 19:01:06 GMT 2025 , Edited by admin on Mon Mar 31 19:01:06 GMT 2025
PRIMARY
ALANWOOD
fluridone
Created by admin on Mon Mar 31 19:01:06 GMT 2025 , Edited by admin on Mon Mar 31 19:01:06 GMT 2025
PRIMARY