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Details

Stereochemistry ACHIRAL
Molecular Formula C19H14F3NO
Molecular Weight 329.3158
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLURIDONE

SMILES

CN1C=C(C2=CC=CC=C2)C(=O)C(=C1)C3=CC(=CC=C3)C(F)(F)F

InChI

InChIKey=YWBVHLJPRPCRSD-UHFFFAOYSA-N
InChI=1S/C19H14F3NO/c1-23-11-16(13-6-3-2-4-7-13)18(24)17(12-23)14-8-5-9-15(10-14)19(20,21)22/h2-12H,1H3

HIDE SMILES / InChI

Molecular Formula C19H14F3NO
Molecular Weight 329.3158
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Fluridone, an herbicide that used for controlling invasive aquatic plants such as hydrilla in surface water bodies. It inhibits carotenoid synthesis in targeted plant species, preventing photosynthesis and ultimately causing mortality. This compound contains a 4(1H)-pyridone and a trifluoromethyl-benzene moiety, which are also present in molecules with analgesic and anti-inflammatory properties. Experiments on rodents have confirmed that fluridone could represent a new prototype of an anti-inflammatory drug.

Approval Year

PubMed

PubMed

TitleDatePubMed
Post-anthesis development of inferior and superior spikelets in rice in relation to abscisic acid and ethylene.
2006
The regulator of G-protein signaling proteins involved in sugar and abscisic acid signaling in Arabidopsis seed germination.
2006 Jan
Gene expression profiles of Arabidopsis Cvi seeds during dormancy cycling indicate a common underlying dormancy control mechanism.
2006 Jun
Aquatic herbicides and herbicide contaminants: In vitro cytotoxicity and cell-cycle analysis.
2006 Jun
Physiological changes in gentian axillary buds during two-step preculturing with sucrose that conferred high levels of tolerance to desiccation and cryopreservation.
2006 Jun
Characterization of a higher plant herbicide-resistant phytoene desaturase and its use as a selectable marker.
2006 Mar
Expression of PsGRP1, a novel glycine rich protein gene of Pisum sativum, is induced in developing fruit and seed and by ABA in pistil and root.
2006 May
Expression of ASCORBATE PEROXIDASE 8 in roots of rice (Oryza sativa L.) seedlings in response to NaCl.
2007
On the role of abscisic acid in seed dormancy of red rice.
2007
Dynamic analysis of ABA accumulation in relation to the rate of ABA catabolism in maize tissues under water deficit.
2007
Cell division versus cell elongation: the control of radicle elongation during thermoinhibition of Tagetes minuta achenes.
2007 Dec
Dissecting the biosynthetic pathway for the bypass1 root-derived signal.
2007 Feb
Ethylene insensitivity results in down-regulation of rubisco expression and photosynthetic capacity in tobacco.
2007 Jul
Gene expression pattern at desiccation in the anther of Lilium longiflorum.
2007 Jul
Strigolactones: promising plant signals.
2007 May
[Study on conditions of seed germination of Cistanche].
2007 Sep
Regulatory involvement of abscisic acid in potato tuber wound-healing.
2008
Tomato strigolactones are derived from carotenoids and their biosynthesis is promoted by phosphate starvation.
2008
Abscisic acid regulates TSRF1-mediated resistance to Ralstonia solanacearum by modifying the expression of GCC box-containing genes in tobacco.
2008
Mutations of genes in synthesis of the carotenoid precursors of ABA lead to pre-harvest sprouting and photo-oxidation in rice.
2008 Apr
Abscisic acid accumulation in the roots of nutrient-limited plants: its impact on the differential growth of roots and shoots.
2008 Aug 25
Involvement of ABA in induction of secondary dormancy in barley (Hordeum vulgare L.) seeds.
2008 Dec
The ABA1 gene and carotenoid biosynthesis are required for late skotomorphogenic growth in Arabidopsis thaliana.
2008 Feb
Abscisic acid controls calcium-dependent egress and development in Toxoplasma gondii.
2008 Jan 10
Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient.
2008 Jun 18
Genetic variation for lettuce seed thermoinhibition is associated with temperature-sensitive expression of abscisic Acid, gibberellin, and ethylene biosynthesis, metabolism, and response genes.
2008 Oct
Assessment of potential aquatic herbicide impacts to California aquatic ecosystems.
2008 Oct
Roles of gibberellins and abscisic acid in dormancy and germination of red bayberry (Myrica rubra) seeds.
2008 Sep
ABA inhibits germination but not dormancy release in mature imbibed seeds of Lolium rigidum Gaud.
2009
The role of ABA in triggering ethylene biosynthesis and ripening of tomato fruit.
2009
ABA, GA(3), and nitrate may control seed germination of Crithmum maritimum (Apiaceae) under saline conditions.
2009 Aug
Cloning and functional analysis of 9-cis-epoxycarotenoid dioxygenase (NCED) genes encoding a key enzyme during abscisic acid biosynthesis from peach and grape fruits.
2009 Aug 15
Abscisic acid negatively regulates elicitor-induced synthesis of capsidiol in wild tobacco.
2009 Jul
Relationship between the degree of carotenoid depletion and function of the photosynthetic apparatus.
2009 Jul 17
Abscisic acid has contrasting effects on salt excretion and polyamine concentrations of an inland and a coastal population of the Mediterranean xero-halophyte species Atriplex halimus.
2009 Oct
Identification and characterization of bZIP-type transcription factors involved in carrot (Daucus carota L.) somatic embryogenesis.
2009 Oct
Nitric oxide mediates the hormonal control of Crassulacean acid metabolism expression in young pineapple plants.
2010 Apr
Arabidopsis RING E3 ligase XBAT32 regulates lateral root production through its role in ethylene biosynthesis.
2010 Aug
Fluridone affects quiescent centre division in the Arabidopsis thaliana root stem cell niche.
2010 Dec
ABA promotes quiescence of the quiescent centre and suppresses stem cell differentiation in the Arabidopsis primary root meristem.
2010 Dec
Carotenoid inhibitors reduce strigolactone production and Striga hermonthica infection in rice.
2010 Dec 1
Storage behavior and changes in concentrations of abscisic acid and gibberellins during dormancy break and germination in seeds of Phellodendron amurense var. wilsonii (Rutaceae).
2010 Feb
Fungal endophytes-induced abscisic acid is required for flavonoid accumulation in suspension cells of Ginkgo biloba.
2010 Feb
A new lead chemical for strigolactone biosynthesis inhibitors.
2010 Jul
A genetic locus and gene expression patterns associated with the priming effect on lettuce seed germination at elevated temperatures.
2010 May
Endogenous abscisic acid as a key switch for natural variation in flooding-induced shoot elongation.
2010 Oct
The plant-specific SR45 protein negatively regulates glucose and ABA signaling during early seedling development in Arabidopsis.
2010 Oct
Initial characterisation of low and high seed dormancy populations of Lolium rigidum produced by repeated selection.
2010 Oct 15
Abscisic acid in salt stress predisposition to phytophthora root and crown rot in tomato and chrysanthemum.
2010 Sep
Fluridone as a new anti-inflammatory drug.
2013 Nov 15
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:02:42 UTC 2023
Edited
by admin
on Fri Dec 15 18:02:42 UTC 2023
Record UNII
3L0JQA61JX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FLURIDONE
HSDB   ISO  
Common Name English
1-METHYL-3-PHENYL-5-(.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)-4-PYRIDONE
Systematic Name English
AVAST
Brand Name English
PRIDE
Brand Name English
FLURIDONE [ISO]
Common Name English
1-METHYL-3-PHENYL-5-(3-(TRIFLUOROMETHYL)PHENYL)-4(1H)-PYRIDINONE
Systematic Name English
EL-171
Code English
FLURIDONE [HSDB]
Common Name English
SONAR
Brand Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 112900
Created by admin on Fri Dec 15 18:02:42 UTC 2023 , Edited by admin on Fri Dec 15 18:02:42 UTC 2023
Code System Code Type Description
HSDB
6653
Created by admin on Fri Dec 15 18:02:42 UTC 2023 , Edited by admin on Fri Dec 15 18:02:42 UTC 2023
PRIMARY
EPA CompTox
DTXSID8024107
Created by admin on Fri Dec 15 18:02:42 UTC 2023 , Edited by admin on Fri Dec 15 18:02:42 UTC 2023
PRIMARY
CAS
59756-60-4
Created by admin on Fri Dec 15 18:02:42 UTC 2023 , Edited by admin on Fri Dec 15 18:02:42 UTC 2023
PRIMARY
FDA UNII
3L0JQA61JX
Created by admin on Fri Dec 15 18:02:42 UTC 2023 , Edited by admin on Fri Dec 15 18:02:42 UTC 2023
PRIMARY
PUBCHEM
43079
Created by admin on Fri Dec 15 18:02:42 UTC 2023 , Edited by admin on Fri Dec 15 18:02:42 UTC 2023
PRIMARY
WIKIPEDIA
Fluridone
Created by admin on Fri Dec 15 18:02:42 UTC 2023 , Edited by admin on Fri Dec 15 18:02:42 UTC 2023
PRIMARY
ECHA (EC/EINECS)
261-916-6
Created by admin on Fri Dec 15 18:02:42 UTC 2023 , Edited by admin on Fri Dec 15 18:02:42 UTC 2023
PRIMARY
ALANWOOD
fluridone
Created by admin on Fri Dec 15 18:02:42 UTC 2023 , Edited by admin on Fri Dec 15 18:02:42 UTC 2023
PRIMARY