U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 00:09:00 GMT 2025
Edited
by admin
on Wed Apr 02 00:09:00 GMT 2025
Protein Type FC FUSION PROTEIN
Protein Sub Type CYTOKINE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
3K3WC6MT6P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EFINEPTAKIN ALFA
INN   USAN  
Official Name English
NT-I7
Preferred Name English
HYLEUKIN
Brand Name English
EFINEPTAKIN ALFA [USAN]
Common Name English
HUMAN FUSION PROTEIN OF METHIONYLGLYCYLMETHIONYL-(1-3)-INTERLEUKIN 7-(4-155)-IMMUNOGLOBULIN HEAVY CONSTANT DELTA IGHD*01 (H1(32-34) H2 CH2(1-11))-(156-193)-IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 4 (CH2(11-110) CH3)-(194-400), DIMER (184-184')-DISULFIDE, PRO
Common Name English
efineptakin alfa [INN]
Common Name English
RECOMBINANT HUMAN IL-7-HYFC (NT-I7)
Common Name English
Efineptakin alfa [WHO-DD]
Common Name English
RECOMBINANT HUMAN INTERLEUKIN-7 FUSED TO A HYBRID CRYSTALLIZABLE FRAGMENT REGION OF A HUMAN ANTIBODY (RHIL-7-HYFC)
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 890122
Created by admin on Wed Apr 02 00:09:00 GMT 2025 , Edited by admin on Wed Apr 02 00:09:00 GMT 2025
FDA ORPHAN DRUG 666218
Created by admin on Wed Apr 02 00:09:00 GMT 2025 , Edited by admin on Wed Apr 02 00:09:00 GMT 2025
FDA ORPHAN DRUG 741620
Created by admin on Wed Apr 02 00:09:00 GMT 2025 , Edited by admin on Wed Apr 02 00:09:00 GMT 2025
Code System Code Type Description
SMS_ID
300000019652
Created by admin on Wed Apr 02 00:09:00 GMT 2025 , Edited by admin on Wed Apr 02 00:09:00 GMT 2025
PRIMARY
FDA UNII
3K3WC6MT6P
Created by admin on Wed Apr 02 00:09:00 GMT 2025 , Edited by admin on Wed Apr 02 00:09:00 GMT 2025
PRIMARY
USAN
HI-213
Created by admin on Wed Apr 02 00:09:00 GMT 2025 , Edited by admin on Wed Apr 02 00:09:00 GMT 2025
PRIMARY
CAS
2026634-47-7
Created by admin on Wed Apr 02 00:09:00 GMT 2025 , Edited by admin on Wed Apr 02 00:09:00 GMT 2025
PRIMARY
INN
10725
Created by admin on Wed Apr 02 00:09:00 GMT 2025 , Edited by admin on Wed Apr 02 00:09:00 GMT 2025
PRIMARY
NCI_THESAURUS
C151927
Created by admin on Wed Apr 02 00:09:00 GMT 2025 , Edited by admin on Wed Apr 02 00:09:00 GMT 2025
PRIMARY
From To
1_5 1_95
1_37 1_132
1_50 1_144
1_214 1_274
1_320 1_378
2_5 2_95
2_37 2_132
2_50 2_144
2_214 2_274
2_320 2_378
1_184 2_184
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_73
N 1_94
N 1_250
N 2_73
N 2_94
N 2_250
O 1_113
O 2_113
Related Record Type Details
INTERLEUKIN-7 RECEPTOR SUBUNIT ALPHA
TARGET -> AGONIST
Related Record Type Details
EFINEPTAKIN ALFA
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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