EFINEPTAKIN ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:32:44 GMT 2023` Edited by `admin` on `Sat Dec 16 14:32:44 GMT 2023`
Protein Type	FC FUSION PROTEIN
Protein Sub Type	CYTOKINE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	3K3WC6MT6P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

EFINEPTAKIN ALFA

Official Name

English

HYLEUKIN

Brand Name

English

EFINEPTAKIN ALFA [USAN]

Common Name

English

HUMAN FUSION PROTEIN OF METHIONYLGLYCYLMETHIONYL-(1-3)-INTERLEUKIN 7-(4-155)-IMMUNOGLOBULIN HEAVY CONSTANT DELTA IGHD*01 (H1(32-34) H2 CH2(1-11))-(156-193)-IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 4 (CH2(11-110) CH3)-(194-400), DIMER (184-184')-DISULFIDE, PRO

Common Name

English

NT-I7

Code

English

efineptakin alfa [INN]

Common Name

English

RECOMBINANT HUMAN IL-7-HYFC (NT-I7)

Common Name

English

Efineptakin alfa [WHO-DD]

Common Name

English

RECOMBINANT HUMAN INTERLEUKIN-7 FUSED TO A HYBRID CRYSTALLIZABLE FRAGMENT REGION OF A HUMAN ANTIBODY (RHIL-7-HYFC)

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

890122

Created by admin on Sat Dec 16 14:32:44 GMT 2023 , Edited by admin on Sat Dec 16 14:32:44 GMT 2023

FDA ORPHAN DRUG

666218

Created by admin on Sat Dec 16 14:32:44 GMT 2023 , Edited by admin on Sat Dec 16 14:32:44 GMT 2023

FDA ORPHAN DRUG

741620

Created by admin on Sat Dec 16 14:32:44 GMT 2023 , Edited by admin on Sat Dec 16 14:32:44 GMT 2023

Code System Code Type Description

FDA UNII

3K3WC6MT6P

Created by admin on Sat Dec 16 14:32:44 GMT 2023 , Edited by admin on Sat Dec 16 14:32:44 GMT 2023

PRIMARY

USAN

HI-213

Created by admin on Sat Dec 16 14:32:44 GMT 2023 , Edited by admin on Sat Dec 16 14:32:44 GMT 2023

PRIMARY

CAS

2026634-47-7

Created by admin on Sat Dec 16 14:32:44 GMT 2023 , Edited by admin on Sat Dec 16 14:32:44 GMT 2023

PRIMARY

INN

10725

Created by admin on Sat Dec 16 14:32:44 GMT 2023 , Edited by admin on Sat Dec 16 14:32:44 GMT 2023

PRIMARY

NCI_THESAURUS

C151927

Created by admin on Sat Dec 16 14:32:44 GMT 2023 , Edited by admin on Sat Dec 16 14:32:44 GMT 2023

PRIMARY

From	To
1_5	1_95
1_37	1_132
1_50	1_144
1_214	1_274
1_320	1_378
2_5	2_95
2_37	2_132
2_50	2_144
2_214	2_274
2_320	2_378
1_184	2_184

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_73
N	1_94
N	1_250
N	2_73
N	2_94
N	2_250
O	1_113
O	2_113

Related Record Type Details


					9J9913QZ47

INTERLEUKIN-7 RECEPTOR SUBUNIT ALPHA

TARGET -> AGONIST

Related Record Type Details


					3K3WC6MT6P

EFINEPTAKIN ALFA

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL