NBI-42902

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H24F3N3O3
Molecular Weight	495.493
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(F)C(=CC=C1)C2=C(C)N(CC3=C(F)C=CC=C3F)C(=O)N(C[C@H](N)C4=CC=CC=C4)C2=O

InChI

InChIKey=CJUWBZDJMYYRDG-QFIPXVFZSA-N

InChI=1S/C27H24F3N3O3/c1-16-24(18-10-6-13-23(36-2)25(18)30)26(34)33(15-22(31)17-8-4-3-5-9-17)27(35)32(16)14-19-20(28)11-7-12-21(19)29/h3-13,22H,14-15,31H2,1-2H3/t22-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C27H24F3N3O3
Molecular Weight	495.493
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Pharmacological characterization of a novel nonpeptide antagonist of the human gonadotropin-releasing hormone receptor, NBI-42902.	2007-02	17095587
Kinetics of nonpeptide antagonist binding to the human gonadotropin-releasing hormone receptor: Implications for structure-activity relationships and insurmountable antagonism.	2006-09-28	16930559

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:07:46 GMT 2025` Edited by `admin` on `Mon Mar 31 22:07:46 GMT 2025`
Record UNII	3FWQ4MD98O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2,4(1H,3H)-PYRIMIDINEDIONE, 3-((2R)-2-AMINO-2-PHENYLETHYL)-1-((2,6-DIFLUOROPHENYL)METHYL)-5-(2-FLUORO-3-METHOXYPHENYL)-6-METHYL-

Preferred Name

English

NBI-42902

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID001352286