AMADINONE ACETATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H27ClO4
Molecular Weight	390.9
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(=O)O[C@@]1(CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C)C(C)=O

InChI

InChIKey=PSJMYDLEWUWIAN-KYPKCDLESA-N

InChI=1S/C22H27ClO4/c1-12(24)22(27-13(2)25)9-7-19-17-11-20(23)18-10-14(26)4-5-15(18)16(17)6-8-21(19,22)3/h10-11,15-17,19H,4-9H2,1-3H3/t15-,16-,17-,19+,21+,22+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C22H27ClO4
Molecular Weight	390.9
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5017374 | https://books.google.ru/books?id=7JPsCAAAQBAJ&pg=PA495&redir_esc=y#v=onepage

Amadione is a steroidal progestogenic antiandrogen. Its anti-androgenic properties were confirmed by blockade of androgen-induced increase in seminal acid phosphatase content.

Approval Year

PubMed

Title	Date	PubMed
Seminal acid phosphatase content in the clinical bioassay of androgens and antiandrogens.	1972-03-01	5017374

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:49:47 GMT 2025` Edited by `admin` on `Mon Mar 31 17:49:47 GMT 2025`
Record UNII	3E13526FYB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AMADINONE ACETATE

Official Name

English

RS-2208

Preferred Name

English

19-NORPREGNA-4,6-DIENE-3,20-DIONE, 17-(ACETYLOXY)-6-CHLORO-

Common Name

English

6-Chloro-17-hydroxy-19-norpregna-4,6-diene-3,20-dione acetate

Common Name

English

AMADINONE ACETATE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C776