AMADINONE ACETATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H27ClO4
Molecular Weight	390.9
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@]3([H])[C@@]4([H])CCC(=O)C=C4C(Cl)=C[C@@]23[H]

InChI

InChIKey=PSJMYDLEWUWIAN-KYPKCDLESA-N

InChI=1S/C22H27ClO4/c1-12(24)22(27-13(2)25)9-7-19-17-11-20(23)18-10-14(26)4-5-15(18)16(17)6-8-21(19,22)3/h10-11,15-17,19H,4-9H2,1-3H3/t15-,16-,17-,19+,21+,22+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C22H27ClO4
Molecular Weight	390.9
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5017374 | https://books.google.ru/books?id=7JPsCAAAQBAJ&pg=PA495&redir_esc=y#v=onepage

Amadione is a steroidal progestogenic antiandrogen. Its anti-androgenic properties were confirmed by blockade of androgen-induced increase in seminal acid phosphatase content.

Approval Year

PubMed

Title	Date	PubMed
Seminal acid phosphatase content in the clinical bioassay of androgens and antiandrogens.	1972 Mar-Apr	5017374

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:11:45 GMT 2023` Edited by `admin` on `Fri Dec 15 15:11:45 GMT 2023`
Record UNII	3E13526FYB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AMADINONE ACETATE

Official Name

English

19-NORPREGNA-4,6-DIENE-3,20-DIONE, 17-(ACETYLOXY)-6-CHLORO-

Common Name

English

6-Chloro-17-hydroxy-19-norpregna-4,6-diene-3,20-dione acetate

Common Name

English

RS-2208

Code

English

AMADINONE ACETATE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C776