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Details

Stereochemistry ACHIRAL
Molecular Formula C3H2F6O
Molecular Weight 168.0378
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,1,1,3,3,3-HEXAFLUOROISOPROPANOL

SMILES

OC(C(F)(F)F)C(F)(F)F

InChI

InChIKey=BYEAHWXPCBROCE-UHFFFAOYSA-N
InChI=1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H

HIDE SMILES / InChI

Molecular Formula C3H2F6O
Molecular Weight 168.0378
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
A screening procedure for the solubilization of chloroplast membrane proteins from the marine green macroalga Ulva lactuca using RP-HPLC-MALDI-MS.
2006-08-15
Biomimetic nanofibrous scaffolds: preparation and characterization of chitin/silk fibroin blend nanofibers.
2006-05-30
Recovery and purification of highly aggregation-prone disulfide-containing peptides: application to islet amyloid polypeptide.
2006-04-15
A new class of glucosidase inhibitor: analogues of the naturally occurring glucosidase inhibitor salacinol with different ring heteroatom substituents and acyclic chain extension.
2006-04-14
1JCH correlates with alcohol hydrogen bond strength.
2006-03-31
Different spectral signatures of octapeptide 3(10)- and alpha-helices revealed by two-dimensional infrared spectroscopy.
2006-03-30
Electrospinning of collagen nanofibers: effects on the behavior of normal human keratinocytes and early-stage wound healing.
2006-03
Methoxy-substituted stilbenes, styrenes, and 1-arylpropenes: photophysical properties and photoadditions of alcohols.
2006-02-17
Solvent effects on the reactivity of fluorenyl nitrenium ion with DNA-like probes.
2006-02-01
Biomimetic nanofibrous scaffolds: preparation and characterization of PGA/chitin blend nanofibers.
2006-02
The alpha-to-beta conformational transition of Alzheimer's Abeta-(1-42) peptide in aqueous media is reversible: a step by step conformational analysis suggests the location of beta conformation seeding.
2006-02
NMR investigation of the dihydrogen-bonding and proton-transfer equilibria between the hydrido carbonyl anion [HRe2(CO)9]- and fluorinated alcohols.
2006-01-23
Film formation and structural characterization of silk of the hornet Vespa simillima xanthoptera Cameron.
2006-01-13
Distinctive influence of two hexafluoro solvents on the structural stabilization of Bombyx mori silk fibroin protein and its derived peptides: 13C NMR and CD studies.
2006-01
HFIP-induced structures and assemblies of the peptides from the transmembrane domain 4 of membrane protein Nramp1.
2006
Novel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease.
2005-12-07
Thermally induced alpha-helix to beta-sheet transition in regenerated silk fibers and films.
2005-11-15
Enhanced phosphopeptide isolation by Fe(III)-IMAC using 1,1,1,3,3,3-hexafluoroisopropanol.
2005-11
Influence of fluoro, chloro and alkyl alcohols on the folding pathway of human serum albumin.
2005-10
Effect of hexafluoroisopropanol alcohol on the structure of melittin: a molecular dynamics simulation study.
2005-10
Hairpin folding dynamics: the cold-denatured state is predisposed for rapid refolding.
2005-08-02
Co-electrospun nanofiber fabrics of poly(L-lactide-co-epsilon-caprolactone) with type I collagen or heparin.
2005-07-12
Amyloid-beta aggregates formed at polar-nonpolar interfaces differ from amyloid-beta protofibrils produced in aqueous buffers.
2005-07
Effect of detergents and hexafluoroisopropanol on the conformation of a non-helical and a helical plant protease inhibitor.
2005-07
Electrospun nano- to microfiber fabrics made of biodegradable copolyesters: structural characteristics, mechanical properties and cell adhesion potential.
2005-06
Synthetic studies toward ecteinascidin 743.
2005-05-27
Characterization of a common intermediate of pea lectin in the folding pathway induced by TFE and HFIP.
2005-05-25
Effects of electrospinning and solution casting protocols on the secondary structure of a genetically engineered dragline spider silk analogue investigated via Fourier transform Raman spectroscopy.
2005-05-10
Enantioselective synthesis of stephacidin B.
2005-04-20
Simultaneous determination of unmodified sevoflurane and of its metabolite hexafluoroisopropanol in urine by headspace sorptive extraction-thermal desorption-capillary gas chromatography-mass spectrometry.
2005-04-15
Deletion of two C-terminal Gln residues of 12-26-residue fragment of melittin improves its antimicrobial activity.
2005-03
Dysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic mice.
2005-02-02
Importance of solubility in the sample preparation of poly(ethylene terephthalate) for MALDI TOFMS.
2005-02-01
Amyloid-beta protofibrils differ from amyloid-beta aggregates induced in dilute hexafluoroisopropanol in stability and morphology.
2005-01-28
Simultaneous determination of pyrethroid and pyrethrin metabolites in human urine by gas chromatography-high resolution mass spectrometry.
2005-01-25
Experimental and computational studies of hydrogen bonding and proton transfer to [Cp*Fe(dppe)H].
2005-01-21
Micellar aggregates formed following the addition of hexafluoroisopropanol to phospholipid membranes.
2005-01-18
Membrane protein and peptide sample handling for MS analysis using a structured MALDI target.
2005-01
Development of an ion-pair reverse-phase liquid chromatographic/tandem mass spectrometry method for the determination of an 18-mer phosphorothioate oligonucleotide in mouse liver tissue.
2005
Comparison of A+T-rich oligonucleotides with and without self-complementary sequence using ion-pair reversed-phase high-performance liquid chromatography/tandem electrospray ionization mass spectrometry.
2005
NMR structures of the C-terminal segment of surfactant protein B in detergent micelles and hexafluoro-2-propanol.
2004-12-07
Alzheimer's beta-peptide oligomer formation at physiologic concentrations.
2004-12-01
Characterization of a partially folded intermediate of papain induced by fluorinated alcohols at low pH.
2004-12-01
1,8-bis(diphenylmethylium)naphthalenediyl dication as an organic oxidant: synthesis of benzidines via self-coupling of N,N-dialkylanilines.
2004-11-25
Fluoroalcohol-induced stabilization of the alpha-helical intermediates of lentil lectin: implication for non-hierarchical lectin folding.
2004-11-15
Anionic contribution for fibrous maturation of protofibrillar assemblies of the human tau repeat domain in a fluoroalcohol solution.
2004-10-26
Rapid characterization of oligonucleotides by capillary liquid chromatography-nano electrospray quadrupole time-of-flight mass spectrometry.
2004-10-15
Understanding the alpha-helix to coil transition in polypeptides using network rigidity: predicting heat and cold denaturation in mixed solvent conditions.
2004-09
Fully-biodegradable poly(3-hydroxybutyrate)/poly(vinyl alcohol) blend films with compositional gradient.
2004-08-09
Hexafluoroisopropanol as size exclusion chromatography mobile phase for polyamide 6.
2004-06
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:09:51 GMT 2025
Edited
by admin
on Mon Mar 31 19:09:51 GMT 2025
Record UNII
3D632GYQ50
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SEVOFLURANE RELATED COMPOUND C
USP-RS  
Preferred Name English
1,1,1,3,3,3-HEXAFLUOROISOPROPANOL
Common Name English
ETHANOL, 2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL)-
Systematic Name English
SEVOFLURANE IMPURITY C [EP IMPURITY]
Common Name English
HEXAFLUORO-2-PROPANOL
Systematic Name English
2-PROPANOL, 1,1,1,3,3,3-HEXAFLUORO-
Systematic Name English
HEXAFLUOROISOPROPYL ALCOHOL
Systematic Name English
BIS(TRIFLUOROMETHYL)METHANOL
Systematic Name English
HEXAFLUOROISOPROPANOL
Systematic Name English
SEVOFLURANE RELATED COMPOUND C [USP-RS]
Common Name English
1,1,1,3,3,3-HEXAFLUOROPROPANOL
Common Name English
2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL)ETHANOL
Systematic Name English
2H-HEXAFLUOROISOPROPANOL
Common Name English
HEXAFLUORO-2-PROPANOL, 1,1,1,3,3,3-
Systematic Name English
1,1,1,3,3,3-HEXAFLUOROISOPROPYL ALCOHOL
Common Name English
NSC-96336
Code English
1,1,1,3,3,3-HEXAFLUORO-2-PROPANOL
Systematic Name English
1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPANE
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID1022134
Created by admin on Mon Mar 31 19:09:51 GMT 2025 , Edited by admin on Mon Mar 31 19:09:51 GMT 2025
PRIMARY
CAS
920-66-1
Created by admin on Mon Mar 31 19:09:51 GMT 2025 , Edited by admin on Mon Mar 31 19:09:51 GMT 2025
PRIMARY
NSC
96336
Created by admin on Mon Mar 31 19:09:51 GMT 2025 , Edited by admin on Mon Mar 31 19:09:51 GMT 2025
PRIMARY
PUBCHEM
13529
Created by admin on Mon Mar 31 19:09:51 GMT 2025 , Edited by admin on Mon Mar 31 19:09:51 GMT 2025
PRIMARY
RS_ITEM_NUM
1612594
Created by admin on Mon Mar 31 19:09:51 GMT 2025 , Edited by admin on Mon Mar 31 19:09:51 GMT 2025
PRIMARY
WIKIPEDIA
Hexafluoroisopropanol
Created by admin on Mon Mar 31 19:09:51 GMT 2025 , Edited by admin on Mon Mar 31 19:09:51 GMT 2025
PRIMARY
FDA UNII
3D632GYQ50
Created by admin on Mon Mar 31 19:09:51 GMT 2025 , Edited by admin on Mon Mar 31 19:09:51 GMT 2025
PRIMARY
ECHA (EC/EINECS)
213-059-4
Created by admin on Mon Mar 31 19:09:51 GMT 2025 , Edited by admin on Mon Mar 31 19:09:51 GMT 2025
PRIMARY
CHEBI
63104
Created by admin on Mon Mar 31 19:09:51 GMT 2025 , Edited by admin on Mon Mar 31 19:09:51 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> METABOLITE
Related Record Type Details
PARENT -> IMPURITY
EP