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Details

Stereochemistry ABSOLUTE
Molecular Formula C12H21O12.C6H11O7.Ca.H2O
Molecular Weight 610.5294
Optical Activity UNSPECIFIED
Defined Stereocenters 13 / 13
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CALCIUM GLUBIONATE

SMILES

C([C@]([H])([C@]([H])([C@@]([H])([C@]([H])(C(=O)[O-])O)O)O[C@@]1([H])[C@@]([H])([C@]([H])([C@]([H])([C@@]([H])(CO)O1)O)O)O)O)O.C([C@]([H])([C@]([H])([C@@]([H])([C@]([H])(C(=O)[O-])O)O)O)O)O.[Ca+2].O

InChI

InChIKey=OKRXSXDSNLJCRS-NLOQLBMISA-L
InChI=1S/C12H22O12.C6H12O7.Ca.H2O/c13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12;7-1-2(8)3(9)4(10)5(11)6(12)13;;/h3-10,12-20H,1-2H2,(H,21,22);2-5,7-11H,1H2,(H,12,13);;1H2/q;;+2;/p-2/t3-,4-,5+,6+,7-,8-,9-,10-,12+;2-,3-,4+,5-;;/m11../s1

HIDE SMILES / InChI

Molecular Formula C6H11O7
Molecular Weight 195.1476
Charge -1
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula Ca
Molecular Weight 40.078
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C12H22O12
Molecular Weight 358.2964
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 9 / 9
E/Z Centers 0
Optical Activity UNSPECIFIED

Calcium iodide (chemical formula CaI2) is the ionic compound of calcium and iodine, used in cat food as a source of iodine This colourless deliquescent solid is a salt that is highly soluble in water. Calcium iodide properties are similar to those for related salts, such as calcium chloride. Calcium iodide is also used in photography.

CNS Activity

Originator

Sources: Helvetica Odontologica Acta (1962), 6, (1), 15-20.https://www.ncbi.nlm.nih.gov/pubmed/16960820

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
elmex

Approved Use

Unknown
Primary
Unknown

Approved Use

Unknown
Palliative
Unknown

Approved Use

Unknown
Palliative
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Hypocalcemia, chronic (treatment) — Oral calcium supplements provide a source of calcium ion for treating calcium depletion occurring in conditions such as chronic hypoparathyroidism, pseudohypoparathyroidism, osteomalacia, rickets, chronic renal failure, and hypocalcemia secondary to the administration of anticonvulsant medications. When chronic hypocalcemia is due to vitamin D deficiency, oral calcium salts may be administered concomitantly with vitamin D analogs. However, calcium phosphate should not be used in patients with hypoparathyroidism or renal failure, since phosphate levels may be too high and giving more phosphate would exacerbate the condition. Calcium supplements should not be used in hyperparathyroidism, unless the need for a calcium supplement is high and the patient is carefully monitored. For treatment of hypocalcemia, supplementation is preferred
PubMed

PubMed

TitleDatePubMed
Studies on the calcemic effect of intravenous secretin in humans.
1975 Jun
Potent inhibition of NFAT activation and T cell cytokine production by novel low molecular weight pyrazole compounds.
2001 Dec 21
Complement activation in factor D-deficient mice.
2001 Dec 4
Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities.
2001 Nov
Activating mutations of the calcium-sensing receptor: management of hypocalcemia.
2001 Nov
Regression of ventral striatum hypometabolism after calcium/calcitriol therapy in paroxysmal kinesigenic choreoathetosis due to idiopathic primary hypoparathyroidism.
2001 Nov
Molecular cloning and functional characterization of murine cysteinyl-leukotriene 1 (CysLT(1)) receptors.
2001 Nov 1
Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide.
2001 Oct
Familial intrahepatic cholestasis 1: studies of localization and function.
2001 Oct
Phosphoinositide 3-kinase isoforms selectively couple receptors to vascular L-type Ca(2+) channels.
2001 Oct 12
Replacement of the muscle-specific sarcoplasmic reticulum Ca(2+)-ATPase isoform SERCA2a by the nonmuscle SERCA2b homologue causes mild concentric hypertrophy and impairs contraction-relaxation of the heart.
2001 Oct 26
Cannabinoids attenuate depolarization-dependent Ca2+ influx in intermediate-size primary afferent neurons of adult rats.
2002
The role of endogenous human Trp4 in regulating carbachol-induced calcium oscillations in HEK-293 cells.
2002 Apr 19
Interaction of intravenous anesthetics with recombinant human M1-M3 muscarinic receptors expressed in chinese hamster ovary cells.
2002 Dec
CXCR4 expression on monocytes is up-regulated by dexamethasone and is modulated by autologous CD3+ T cells.
2002 Feb
Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene.
2002 Feb
Characterization of basolateral K+ channels underlying anion secretion in the human airway cell line Calu-3.
2002 Feb 1
Prostaglandin E(2) protects intestinal tumors from nonsteroidal anti-inflammatory drug-induced regression in Apc(Min/+) mice.
2002 Jan 15
Characterization of the bone-resorptive effect of interleukin-11 in cultured mouse calvarial bones.
2002 Jul
Delayed asystolic cardiac arrest after diltiazem overdose; resuscitation with high dose intravenous calcium.
2002 Jul
Transcriptional induction of CYP1A1 by oltipraz in human Caco-2 cells is aryl hydrocarbon receptor- and calcium-dependent.
2002 Jul 5
Human kidney diamine oxidase: heterologous expression, purification, and characterization.
2002 Jun
Expression of functional CCR and CXCR chemokine receptors in podocytes.
2002 Jun 15
Investigation of a functional requirement for isoprenylation by the human prostacyclin receptor.
2002 Mar
Hypertension-related intermyocyte junction remodelling is associated with a higher incidence of low-K(+)-induced lethal arrhythmias in isolated rat heart.
2002 Mar
Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.
2002 Mar 15
Diacylglycerol activates the influx of extracellular cations in T-lymphocytes independently of intracellular calcium-store depletion and possibly involving endogenous TRP6 gene products.
2002 May 15
Neuronal apoptosis inhibitory protein: Structural requirements for hippocalcin binding and effects on survival of NGF-dependent sympathetic neurons.
2002 Nov 4
Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit.
2002 Sep
Inhibition of peroxisome proliferator-activated receptor (PPAR)-mediated keratinocyte differentiation by lipoxygenase inhibitors.
2002 Sep 15
Effects of endothelin B receptor agonists on amyloid beta protein (25-35)-induced neuronal cell death.
2002 Sep 6
A critical interplay between Ca2+ inhibition and activation by Mg2+ of AC5 revealed by mutants and chimeric constructs.
2002 Sep 6
Mechanism of enhanced calcium sensitivity and alpha 2-AR vasoreactivity in chronic NOS inhibition hypertension.
2003 Jan
An improved method for emergent decontamination of ocular and dermal hydrofluoric acid splashes.
2004 Aug
Epidemiology of 377 patients with chemical burns in Guangdong province.
2004 Sep
[Prevention of osteoporosis by foods and dietary supplements. Bioavailability of milk micellar calcium phosphate].
2006 Oct
Henri Moissan: winner of the Nobel Prize for Chemistry 1906.
2006 Oct 20
Successful extracorporeal life support after potentially fatal pulmonary oedema caused by inhalation of nitric and hydrofluoric acid fumes.
2007 Oct
Dietary calcium source influences body composition, glucose metabolism and hormone levels in a mouse model of postmenopausal obesity.
2009 Jul-Aug
A combination of calcium phosphate and probiotics beneficially influences intestinal lactobacilli and cholesterol metabolism in humans.
2012 Apr
Sensitivity of human dental pulp cells to eighteen chemical agents used for endodontic treatments in dentistry.
2013 Jan
Effect of calcium phosphate and vitamin D₃ supplementation on bone remodelling and metabolism of calcium, phosphorus, magnesium and iron.
2014 Jan 17
Long-term remineralizing effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on early caries lesions in vivo: a systematic review.
2014 Jul
Oleylamine as a beneficial agent for the synthesis of CoFe₂O₄ nanoparticles with potential biomedical uses.
2014 May 7
Efficacy and safety of inhaled calcium lactate PUR118 in the ozone challenge model--a clinical trial.
2015 Aug 12
Cytotoxicity of organic surface coating agents used for nanoparticles synthesis and stability.
2015 Jun
Dietary interventions for mineral and bone disorder in people with chronic kidney disease.
2015 Sep 16
Lactose behaviour in the presence of lactic acid and calcium.
2016 Aug
Allergic contact cheilitis caused by olaflur in toothpaste.
2017 Jan
Effects of ultrasound treatment on physico-chemical, functional properties and antioxidant activity of whey protein isolate in the presence of calcium lactate.
2018 Mar
Patents

Patents

Sample Use Guides

toxicity in mice: LD50 = 888 mg/kg
Route of Administration: Intraperitoneal
Cytotoxicity study: it was explored the cytotoxicity of the coating agent, Oleylamine in two cell lines, human epidermal keratinocyte (HaCaT) and lung fibroblast (CRL-1490) cells, at surface coating agent concentrations of 3, 10, 30, and 100 μM. Two exposure time points, 2 h, and 24 h were employed for the study. Oleylamine, is highly toxic, leading to almost 100% cell death.
Substance Class Chemical
Created
by admin
on Sat Jun 26 06:36:45 UTC 2021
Edited
by admin
on Sat Jun 26 06:36:45 UTC 2021
Record UNII
3CF7K0SD0Q
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CALCIUM GLUBIONATE
INN   MART.   USAN   USP   VANDF   WHO-DD  
INN   USAN  
Official Name English
CALCIUM GLUCONOGALACTOGLUCONATE
Common Name English
NEO-CALGLUCON
Brand Name English
CALCIUM, (4-O-.BETA.-D-GALACTOPYRANOSYL-D-GLUCONATO)(D-GLUCONATO)-, MONOHYDRATE
Common Name English
CALCIUM GLUBIONATE [INN]
Common Name English
CALCIUM D-GLUCONATE LACTOBIONATE MONOHYDRATE
Common Name English
GLUBIONATE CALCIUM
Common Name English
CALCIUM GLUBIONATE [MART.]
Common Name English
CALCIUM GLUBIONATE [USAN]
Common Name English
CALCIUM, (4-O-.BETA.-D-GALACTOPYRANOSYL-D-GLUCONATO-O(SUP 1))(D-GLUCONATO-O(SUP 1))-, MONOHYDRATE
Common Name English
CALCIUM GLUBIONATE [VANDF]
Common Name English
CALCIUM GLUBIONATE [USP]
Common Name English
(D-GLUCONATO)(LACTOBIONATO)CALCIUM MONOHYDRATE
Common Name English
CALCIUM GLUBIONATE [WHO-DD]
Common Name English
Classification Tree Code System Code
WHO-ATC A12AA02
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
WHO-VATC QA12AA02
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
Code System Code Type Description
NCI_THESAURUS
C166669
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
PRIMARY
DRUG BANK
DBSALT001951
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
PRIMARY
CAS
12569-38-9
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
PRIMARY
WIKIPEDIA
CALCIUM GLUBIONATE
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
PRIMARY
MESH
C042131
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
PRIMARY
RXCUI
25806
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
PRIMARY RxNorm
EVMPD
SUB06053MIG
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
PRIMARY
PUBCHEM
25557
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
PRIMARY
ChEMBL
CHEMBL2219740
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
PRIMARY
FDA UNII
3CF7K0SD0Q
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
PRIMARY
DRUG CENTRAL
4842
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
PRIMARY
INN
2890
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
PRIMARY
EVMPD
SUB126888
Created by admin on Sat Jun 26 06:36:46 UTC 2021 , Edited by admin on Sat Jun 26 06:36:46 UTC 2021
ALTERNATIVE
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE