FLETAZEPAM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H13ClF4N2
Molecular Weight	356.745
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC1=CC=CC=C1C2=NCCN(CC(F)(F)F)C3=CC=C(Cl)C=C23

InChI

InChIKey=CIZCSUNUBQXVFP-UHFFFAOYSA-N

InChI=1S/C17H13ClF4N2/c18-11-5-6-15-13(9-11)16(12-3-1-2-4-14(12)19)23-7-8-24(15)10-17(20,21)22/h1-6,9H,7-8,10H2

HIDE SMILES / InChI

Molecular Formula	C17H13ClF4N2
Molecular Weight	356.745
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/mesh/67009754 | https://www.ncbi.nlm.nih.gov/pubmed/4476200

FLETAZEPAM, a benzodiazepine derivative, is a centrally-acting muscle relaxant more effective than diazepam in preventing convulsions and muscle rigidity.

Approval Year

PubMed

Title	Date	PubMed
Selective affinity of 1-N-trifluoroethyl benzodiazepines for cerebellar type 1 receptor sites.	1984-07-02	6738302
The pharmacology of fletazepam a centrally-acting muscle relaxant.	1974-11	4476200

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:57:58 GMT 2025` Edited by `admin` on `Mon Mar 31 17:57:58 GMT 2025`
Record UNII	3AH8OSQ79O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLETAZEPAM

Official Name

English

SCH 15698

Preferred Name

English

FLETAZEPAM [USAN]

Common Name

English

1H-1,4-BENZODIAZEPINE, 7-CHLORO-5-(2-FLUOROPHENYL)-2,3-DIHYDRO-1-(2,2,2-TRIFLUOROETHYL)-

Systematic Name

English

SCH-15698

Code

English

7-CHLORO-5-(O-FLUOROPHENYL)-2,3-DIHYDRO-1-(2,2,2-TRIFLUOROETHYL)-1H-1,4-BENZODIAZEPINE

Common Name

English

fletazepam [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1012