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Details

Stereochemistry ACHIRAL
Molecular Formula C23H15N3O2
Molecular Weight 365.385
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DESPYRIDINYL-(5-HYDROXYPYRIDIN-2-YL)PERAMPANEL

SMILES

c1ccc(cc1)-n2cc(cc(-c3ccccc3C#N)c2=O)-c4ccc(cn4)O

InChI

InChIKey=ANABGQBVYPBTIS-UHFFFAOYSA-N
InChI=1S/C23H15N3O2/c24-13-16-6-4-5-9-20(16)21-12-17(22-11-10-19(27)14-25-22)15-26(23(21)28)18-7-2-1-3-8-18/h1-12,14-15,27H

HIDE SMILES / InChI

Molecular Formula C23H15N3O2
Molecular Weight 365.385
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Substance Class Chemical
Created
by admin
on Sat Jun 26 16:19:41 UTC 2021
Edited
by admin
on Sat Jun 26 16:19:41 UTC 2021
Record UNII
3A2H7791I2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DESPYRIDINYL-(5-HYDROXYPYRIDIN-2-YL)PERAMPANEL
Common Name English
BENZONITRILE, 2-(1',6'-DIHYDRO-5-HYDROXY-6'-OXO-1'-PHENYL(2,3'-PYRIDINE)-5'-YL)-
Systematic Name English
PERAMPANEL METABOLITE M1
Common Name English
3-(2-CYANOPHENYL)-5-(5-HYDROXYPYRIDIN-2-YL)-1-PHENYL-1,2-DIHYDROPYRIDIN-2-ONE
Systematic Name English
Code System Code Type Description
CAS
380919-57-3
Created by admin on Sat Jun 26 16:19:42 UTC 2021 , Edited by admin on Sat Jun 26 16:19:42 UTC 2021
PRIMARY
PUBCHEM
22319219
Created by admin on Sat Jun 26 16:19:42 UTC 2021 , Edited by admin on Sat Jun 26 16:19:42 UTC 2021
PRIMARY
FDA UNII
3A2H7791I2
Created by admin on Sat Jun 26 16:19:42 UTC 2021 , Edited by admin on Sat Jun 26 16:19:42 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> METABOLITE INACTIVE
In vitro studies show that the primary oxidative metabolic route of perampanel is via cytochrome P450 (CYP)3A4 and/or CYP3A5, based on the results of metabolism by recombinant human CYPs, and inhibition studies using anti-CYP3A4 and ketoconazole in human liver microsomes.
FECAL; URINE