BUTONATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C8H14Cl3O5P
Molecular Weight	327.527
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCC(=O)OC(C(Cl)(Cl)Cl)P(=O)(OC)OC

InChI

InChIKey=BKAQXYNWONVOAX-UHFFFAOYSA-N

InChI=1S/C8H14Cl3O5P/c1-4-5-6(12)16-7(8(9,10)11)17(13,14-2)15-3/h7H,4-5H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C8H14Cl3O5P
Molecular Weight	327.527
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4747043

Butonate is a veterinary anti-parasitic drug, which was approved by FDA, but lately voluntarily withdrawn.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Helminth infection 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/4747043	Curative		Approved 8583	VET KEM T-113 Approved Use Unknown

PubMed

Title	Date	PubMed
Activity of organophosphorus insecticides in bacterial tests for mutagenicity and DNA repair--direct alkylation vs. metabolic activation and breakdown. I. Butonate, vinylbutonate, trichlorfon, dichlorvos, demethyl dichlorvos and demethyl vinylbutonate.	1982-04	7074710
Critical tests of an orally administered butonate as an anthelmintic in horses.	1973-09	4747043
Critical tests of butonate as an ascaricide and boticide in horses.	1971-12	5167171
[Studies on the application of the low toxicity 32P- labeled phosphonic acid ester, Butonate, in cattle].	1967	5598567

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:18:02 GMT 2025` Edited by `admin` on `Mon Mar 31 18:18:02 GMT 2025`
Record UNII	39M9R3Q494
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TRICHLORFON BUTANOIC ACID ESTER

Preferred Name

English

BUTONATE

Official Name

English

(RS)-2,2,2-TRICHLORO-1-(DIMETHOXYPHOSPHINOYL)ETHYL BUTYRATE

Systematic Name

English

butonate [INN]

Common Name

English

NSC-17872

Code

English

TRICHLORFON BUTANOIC ACID ESTER [MI]

Common Name

English

BUTONATE [ISO]

Common Name

English

Butyric acid, ester with dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate

Common Name

English

BUTONATE [GREEN BOOK]

Common Name

English

BUTANOIC ACID, 2,2,2-TRICHLORO-1-(DIMETHOXYPHOSPHINYL)ETHYL ESTER

Common Name

English

BUTONATE [HSDB]

Common Name

English

O,O-DIMETHYL (2,2,2-TRICHLORO-1-N-BUTYRYLOXYETHYL)PHOSPHONATE

Common Name

English

BUTONATE [USAN]

Common Name

English

ENT-20852

Code

English

2,2,2-TRICHLORO-1-(DIMETHOXYPHOSPHINYL)ETHYL BUTANOATE

Systematic Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

35701