SODIUM CHANNEL PROTEIN TYPE 8 SUBUNIT ALPHA

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 18:54:26 GMT 2025` Edited by `admin` on `Tue Apr 01 18:54:26 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	39G0G4XQ32
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MED

Preferred Name

English

SODIUM CHANNEL PROTEIN TYPE 8 SUBUNIT ALPHA

Common Name

English

VOLTAGE-GATED SODIUM CHANNEL SUBUNIT ALPHA NAV1.6

Common Name

English

SODIUM CHANNEL PROTEIN TYPE VIII SUBUNIT ALPHA

Common Name

English

Code System Code Type Description

FDA UNII

39G0G4XQ32

Created by admin on Tue Apr 01 18:54:26 GMT 2025 , Edited by admin on Tue Apr 01 18:54:26 GMT 2025

PRIMARY

WIKIPEDIA

SCN8A

Created by admin on Tue Apr 01 18:54:26 GMT 2025 , Edited by admin on Tue Apr 01 18:54:26 GMT 2025

PRIMARY

UNIPROT

Q9UQD0

Created by admin on Tue Apr 01 18:54:26 GMT 2025 , Edited by admin on Tue Apr 01 18:54:26 GMT 2025

PRIMARY

PHAROS

Q9UQD0

Created by admin on Tue Apr 01 18:54:26 GMT 2025 , Edited by admin on Tue Apr 01 18:54:26 GMT 2025

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_215
N	1_289
N	1_295
N	1_308
N	1_326
N	1_1358
N	1_1372
N	1_1383

Related Record Type Details


					SV2WPA4R4J

Zandatrigine

INHIBITOR -> TARGET

Comments:

Remarkably selective for the NaV1.6 sodium channel over other isoforms (IC50 = 51 nM, 756x vs. NaV1.1, 134X vs. NaV1.2, 276X vs. NaV1.7, >583X vs. 1.3, 1.4, 1.5.

Amount: