Puxitatug Samrotecan

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 10:37:35 GMT 2025` Edited by `admin` on `Wed Apr 02 10:37:35 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	396QL65J3Q
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AZD-8205

Preferred Name

English

Puxitatug Samrotecan

Official Name

English

puxitatug samrotecan [INN]

Common Name

English

Immunoglobulin G1, anti-(human B7 homolog 4 protein) (human monoclonal INT-016 ?1-chain), disulfide with human monoclonal INT-016 ?-chain, dimer, reduced, 214??,214???,220,220?,226,226?,229,229?-octakis(thioether) with N-[31-(3-mercapto-2,5-dioxo-3-pyrro

Common Name

English

PUXITATUG SAMROTECAN [USAN]

Common Name

English

AZD8205

Code

English

immunoglobulin G1-kappa, anti-[Homo sapiens VTCN1 (V-set domain containing T cell activation inhibitor 1, B7 family member H4, B7H4, B7-H4)], Homo sapiens monoclonal antibody; conjugated to a topoisomerase I inhibitor (gamma1 heavy chain Homo sapiens (1-

Common Name

English

Code System Code Type Description

INN

12513

Created by admin on Wed Apr 02 10:37:35 GMT 2025 , Edited by admin on Wed Apr 02 10:37:35 GMT 2025

PRIMARY

NCI_THESAURUS

C199096

Created by admin on Wed Apr 02 10:37:35 GMT 2025 , Edited by admin on Wed Apr 02 10:37:35 GMT 2025

PRIMARY

USAN

MN-78

Created by admin on Wed Apr 02 10:37:35 GMT 2025 , Edited by admin on Wed Apr 02 10:37:35 GMT 2025

PRIMARY

FDA UNII

396QL65J3Q

Created by admin on Wed Apr 02 10:37:35 GMT 2025 , Edited by admin on Wed Apr 02 10:37:35 GMT 2025

PRIMARY

CAS

2760250-80-2

Created by admin on Wed Apr 02 10:37:35 GMT 2025 , Edited by admin on Wed Apr 02 10:37:35 GMT 2025

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SMS_ID

300000048732

Created by admin on Wed Apr 02 10:37:35 GMT 2025 , Edited by admin on Wed Apr 02 10:37:35 GMT 2025

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From	To
1_22	1_95
2_22	2_95
2_144	2_200
2_261	2_321
1_144	1_200
2_367	2_425
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_261	1_321
1_367	1_425

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_52
N	1_297
N	2_52
N	2_297

Related Record Type Details


					ZZ6R8M49EG

Puxitatug

PARENT -> CONJUGATE

Amount:

Related Record Type Details


					396QL65J3Q

Puxitatug Samrotecan

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL