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Details

Stereochemistry RACEMIC
Molecular Formula C5H11NO2S.ClH
Molecular Weight 185.672
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RACEMETHIONINE HYDROCHLORIDE

SMILES

Cl.CSCCC(N)C(O)=O

InChI

InChIKey=OSUIUMQSEFFIKM-UHFFFAOYSA-N
InChI=1S/C5H11NO2S.ClH/c1-9-3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8);1H

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C5H11NO2S
Molecular Weight 149.211
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

DL-Methionine is a racemic form of the respective sulfur aminoacid. DL-Methionine participates in synthesis of tissue proteins, vitamins, enzymes and hormones taking part in nitrogen, carbohydrate and fat metabolisms, and it is the important source of methyl groups for synthesis of all nucleic acids, as well as the sulfur source for sulfonic compounds. Methionine is used to prevent liver damage in acetaminophen (Tylenol) poisoning. It is also used for increasing the acidity of urine, treating liver disorders, and improving wound healing. Other uses include treating depression, alcoholism, allergies, asthma, copper poisoning, radiation side effects, schizophrenia, drug withdrawal, and Parkinson's disease. It is also used as a food additive in livestock to boost performance. DL-Methionin is the first limiting amino acid in poultry, and probably also in high-yielding cows, and is the second or third limiting amino acid in pigs fed conventional diets.

Approval Year

Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Novel mutations in the GALK1 gene in patients with galactokinase deficiency.
2001
Saccharomyces cerevisiae is capable of de Novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine.
2001 Apr 6
A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria.
2001 Feb
Elevation of asymmetrical dimethylarginine may mediate endothelial dysfunction during experimental hyperhomocyst(e)inaemia in humans.
2001 Feb
The folate cycle and disease in humans.
2001 Feb
Extracellular amino acid profiles in the paraventricular nucleus of the rat hypothalamus are influenced by diet composition.
2001 Feb 23
A 7-kDa prion protein (PrP) fragment, an integral component of the PrP region required for infectivity, is the major amyloid protein in Gerstmann-Sträussler-Scheinker disease A117V.
2001 Feb 23
Steroidogenic acute regulatory protein expression is dependent upon post-translational effects of cAMP-dependent protein kinase A.
2001 Feb 28
Near-infrared reflectance spectroscopy enables the fast and accurate prediction of the essential amino acid contents in soy, rapeseed meal, sunflower meal, peas, fishmeal, meat meal products, and poultry meal.
2001 Jan
Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens: a comparison with opioids.
2001 Jan
Intestinal apical amino acid absorption during development of the pig.
2001 Jan
The role of pyridoxal phosphate in the function of EspB, a protein secreted by enteropathogenic Escherichia coli.
2001 Jan 12
Increased susceptibility to Kuru of carriers of the PRNP 129 methionine/methionine genotype.
2001 Jan 15
The effects of processing methods on the levels of lysine, methionine and the general acceptability of ogi processed using starter cultures.
2001 Jan 22
The additional methionine residue at the N-terminus of bacterially expressed human interleukin-2 affects the interaction between the N- and C-termini.
2001 Jan 30
Crystallization and preliminary X-ray crystallographic studies of recombinant human betaine-homocysteine S-methyltransferase.
2001 Mar
Synthesis of active high mannose-type lipoprotein lipase in human adipose tissues.
2001 Mar
Inhibitory effect of reactive oxygen species on angiotensin I-converting enzyme (kininase II).
2001 Mar
The effects of oral methionine and homocysteine on endothelial function.
2001 Mar
Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine, and ascorbate.
2001 Mar 1
Relative reactivities of N-chloramines and hypochlorous acid with human plasma constituents.
2001 Mar 1
Thermodynamics of the helix-coil transition: Binding of S15 and a hybrid sequence, disulfide stabilized peptide to the S-protein.
2001 Mar 1
Axon terminals containing CGRP-immunoreactivity form synapses with CRF- and Met-enkephalin-immunopositive neurons in the laterodorsal division of the bed nucleus of the stria terminalis in the rat.
2001 Mar 2
Uptake of tritiated thymidine, deoxyglucose and methionine in three lung cancer cell lines: deoxyglucose uptake mirrors tritiated thymidine uptake.
2001 Mar-Apr
Patents

Sample Use Guides

For acetaminophen (Tylenol) poisoning: 2.5 grams of methionine every 4 hours for 4 doses to prevent liver damage and death. Methionine must be given within 10 hours of taking the acetaminophen.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Thu Jul 06 16:02:29 UTC 2023
Edited
by admin
on Thu Jul 06 16:02:29 UTC 2023
Record UNII
38WFI1311A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RACEMETHIONINE HYDROCHLORIDE
Common Name English
DL-METHIONINE HYDROCHLORIDE
Systematic Name English
METHIONINE HYDROCHLORIDE, DL
Common Name English
Code System Code Type Description
EVMPD
SUB129679
Created by admin on Thu Jul 06 16:02:29 UTC 2023 , Edited by admin on Thu Jul 06 16:02:29 UTC 2023
PRIMARY
FDA UNII
38WFI1311A
Created by admin on Thu Jul 06 16:02:29 UTC 2023 , Edited by admin on Thu Jul 06 16:02:29 UTC 2023
PRIMARY
SMS_ID
100000155643
Created by admin on Thu Jul 06 16:02:29 UTC 2023 , Edited by admin on Thu Jul 06 16:02:29 UTC 2023
PRIMARY
PUBCHEM
10219725
Created by admin on Thu Jul 06 16:02:29 UTC 2023 , Edited by admin on Thu Jul 06 16:02:29 UTC 2023
PRIMARY
CAS
37622-81-4
Created by admin on Thu Jul 06 16:02:29 UTC 2023 , Edited by admin on Thu Jul 06 16:02:29 UTC 2023
PRIMARY
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