TRALONIDE

Possibly Marketed Outside US

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H28Cl2F2O4
Molecular Weight	489.38
Optical Activity	UNSPECIFIED
Defined Stereocenters	9 / 9
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(Cl)[C@@H](Cl)C[C@]3(C)[C@@]2(O1)C(=O)CF

InChI

InChIKey=OGZHZYVCWDUIJV-VSXGLTOVSA-N

InChI=1S/C24H28Cl2F2O4/c1-20(2)31-19-9-13-14-8-16(28)15-7-12(29)5-6-21(15,3)23(14,26)17(25)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C24H28Cl2F2O4
Molecular Weight	489.38
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	9 / 9
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5000463 | https://books.google.ru/books?id=-DZRx_kaaCMC&pg=PA267&lpg=PA267&dq=TRALONIDE&source=bl&ots=TbOHzZH1qL&sig=ACfU3U2NplBCzMeX46AWUUzxvyclRQ9BJA&hl=ru&sa=X&ved=2ahUKEwjHt_Wd56_hAhUhpIsKHe2ODcw4ChDoATAFegQICRAB#v=onepage&q=TRALONIDE&f=false

Tralonide, a new topical steroid, can be used in atopic dermatitis.

Approval Year

PubMed

Title	Date	PubMed
Clinical evaluation of tralonide ointment, a new topical steroid.	1971-09	5000463

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Topical

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:08:37 GMT 2025` Edited by `admin` on `Mon Mar 31 18:08:37 GMT 2025`
Record UNII	38ETX8IT42
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

9,11?-Dichloro-6?,21-difluoro-16?,17-dihydroxypregna-1,4-diene-3,20-dione cyclic acetal with acetone

Preferred Name

English

TRALONIDE

Official Name

English

PREGNA-1,4-DIENE-3,20-DIONE, 9,11-DICHLORO-6,21-DIFLUORO-16,17-((1-METHYLETHYLIDENE)BIS(OXY))(6.ALPHA.,11.BETA.,16.ALPHA.)-

Common Name

English

tralonide [INN]

Common Name

English

TRALONIDE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C521