Leramistat

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H21ClN2O3S
Molecular Weight	404.91
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@]1(O)CC[C@@H](CC1)NS(=O)(=O)C2=CC=C(C=C2)C3=C(C=C(Cl)C=C3)C#N

InChI

InChIKey=PHOYDFRXZMNHIF-IRJFHVNHSA-N

InChI=1S/C20H21ClN2O3S/c1-20(24)10-8-17(9-11-20)23-27(25,26)18-5-2-14(3-6-18)19-7-4-16(21)12-15(19)13-22/h2-7,12,17,23-24H,8-11H2,1H3/t17-,20-

HIDE SMILES / InChI

Molecular Formula	C20H21ClN2O3S
Molecular Weight	404.91
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:20:14 GMT 2023` Edited by `admin` on `Sat Dec 16 18:20:14 GMT 2023`
Record UNII	38E2HYD3AW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Leramistat

Official Name

English

4'-chloro-2'-cyano-N-(trans-4-hydroxy-4-methylcyclohexyl)-biphenyl-4-sulfonamide

Systematic Name

English

4'-chloro-2'-cyano-N-[(1r,4r)-4-hydroxy-4-methylcyclohexyl][1,1'-biphenyl]-4-sulfonamide

Systematic Name

English

HMC-C-01-A

Code

English

leramistat [INN]

Common Name

English

MBS-2320

Code

English

1-METHYL-TRANS-4-(((4'-CHLORO-2'-CYANO-1,1'-BIPHENYL-4-YL)SULFONYL)AMINO)CYCLOHEXANOL

Systematic Name

English

(1,1'-BIPHENYL)-4-SULFONAMIDE, 4'-CHLORO-2'-CYANO-N-(TRANS-4-HYDROXY-4-METHYLCYCLOHEXYL)-

Systematic Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

894922

Created by admin on Sat Dec 16 18:20:14 GMT 2023 , Edited by admin on Sat Dec 16 18:20:14 GMT 2023

Code System Code Type Description

FDA UNII

38E2HYD3AW

Created by admin on Sat Dec 16 18:20:14 GMT 2023 , Edited by admin on Sat Dec 16 18:20:14 GMT 2023

PRIMARY

INN

12718

Created by admin on Sat Dec 16 18:20:14 GMT 2023 , Edited by admin on Sat Dec 16 18:20:14 GMT 2023

PRIMARY

CAS

1642602-54-7

Created by admin on Sat Dec 16 18:20:14 GMT 2023 , Edited by admin on Sat Dec 16 18:20:14 GMT 2023

PRIMARY

Related Record Type Details


					38E2HYD3AW

Leramistat

ACTIVE MOIETY

Comments:

MBS2320 is a first-in-class modulator of mitochondrial complex I which exhibits a cell pathology profile consistent with the maintenance of normal alveolar epithelial repair. MBS2320 has an anti-proliferative effect on activated fibroblasts and

Interaction Type:

PRECLINICAL

Amount: