Details
Stereochemistry | ACHIRAL |
Molecular Formula | C16H23NO3 |
Molecular Weight | 277.3587 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC(=CC=C1)C(=O)OCCCN2CCCCC2
InChI
InChIKey=MDEHCYRQFACAGY-UHFFFAOYSA-N
InChI=1S/C16H23NO3/c1-19-15-8-5-7-14(13-15)16(18)20-12-6-11-17-9-3-2-4-10-17/h5,7-8,13H,2-4,6,9-12H2,1H3
Molecular Formula | C16H23NO3 |
Molecular Weight | 277.3587 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Pribecaine (also known as RG-1812 ) is 3-methoxy-benzoic acid derivative patented by Hungarian multinational pharmaceutical and biotech company Richter, Gedeon, Vegyeszeti Gyar Rt. as local anesthetics. Pribecaine inhibited the generation of action potentials in the giant neurons of the mollusk (Lymnaea stagnalis) and prevented the excitatory effect of acetylcholine. During the inhibition of action potential, the rising phase and repolarization were simultaneously damaged, indicating a blockade of both the Na- and K-channels.
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 17:24:17 GMT 2023
by
admin
on
Sat Dec 16 17:24:17 GMT 2023
|
Record UNII |
382TLA8X28
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
NCI_THESAURUS |
C245
Created by
admin on Sat Dec 16 17:24:17 GMT 2023 , Edited by admin on Sat Dec 16 17:24:17 GMT 2023
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
100000081631
Created by
admin on Sat Dec 16 17:24:17 GMT 2023 , Edited by admin on Sat Dec 16 17:24:17 GMT 2023
|
PRIMARY | |||
|
3050427
Created by
admin on Sat Dec 16 17:24:17 GMT 2023 , Edited by admin on Sat Dec 16 17:24:17 GMT 2023
|
PRIMARY | |||
|
55837-22-4
Created by
admin on Sat Dec 16 17:24:17 GMT 2023 , Edited by admin on Sat Dec 16 17:24:17 GMT 2023
|
PRIMARY | |||
|
DTXSID30204433
Created by
admin on Sat Dec 16 17:24:17 GMT 2023 , Edited by admin on Sat Dec 16 17:24:17 GMT 2023
|
PRIMARY | |||
|
3645
Created by
admin on Sat Dec 16 17:24:17 GMT 2023 , Edited by admin on Sat Dec 16 17:24:17 GMT 2023
|
PRIMARY | |||
|
SUB10034MIG
Created by
admin on Sat Dec 16 17:24:17 GMT 2023 , Edited by admin on Sat Dec 16 17:24:17 GMT 2023
|
PRIMARY | |||
|
CHEMBL2105314
Created by
admin on Sat Dec 16 17:24:17 GMT 2023 , Edited by admin on Sat Dec 16 17:24:17 GMT 2023
|
PRIMARY | |||
|
382TLA8X28
Created by
admin on Sat Dec 16 17:24:17 GMT 2023 , Edited by admin on Sat Dec 16 17:24:17 GMT 2023
|
PRIMARY | |||
|
C66467
Created by
admin on Sat Dec 16 17:24:17 GMT 2023 , Edited by admin on Sat Dec 16 17:24:17 GMT 2023
|
PRIMARY |
Related Record | Type | Details | ||
---|---|---|---|---|
|
ACTIVE MOIETY |