U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula CHO2.H4N
Molecular Weight 63.0559
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMMONIUM FORMATE

SMILES

[NH4+].[O-]C=O

InChI

InChIKey=VZTDIZULWFCMLS-UHFFFAOYSA-N
InChI=1S/CH2O2.H3N/c2-1-3;/h1H,(H,2,3);1H3

HIDE SMILES / InChI

Molecular Formula CH2O2
Molecular Weight 46.0254
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula H3N
Molecular Weight 17.0305
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Formic acid is the simplest carboxylic acid. In nature, formic acid is found in the stings and bites of many insects of the order Hymenoptera, including bees and ants. The principal use of formic acid is as a preservative and antibacterial agent in livestock feed. When sprayed on fresh hay or other silage, it arrests certain decay processes and causes the feed to retain its nutritive value longer. In medicine 85% formic acid application is a safe, economical, and effective alternative in the treatment of common warts with few side-effects and good compliance.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
EndWarts PEN

Approved Use

EndWarts PEN is a unique and effective wart treatment
PubMed

PubMed

TitleDatePubMed
Controlled proteolysis of amelogenins reveals exposure of both carboxy- and amino-terminal regions.
2001-06
Crystal structure of activated CheY. Comparison with other activated receiver domains.
2001-05-11
Mouse MCT3 gene is expressed preferentially in retinal pigment and choroid plexus epithelia.
2001-05
Diet-induced ketosis increases monocarboxylate transporter (MCT1) levels in rat brain.
2001-05
Targeting of calsequestrin to the sarcoplasmic reticulum of skeletal muscle upon deletion of its glycosylation site.
2001-04-15
Functional proteins from a random-sequence library.
2001-04-05
Long-lived glycosyl-enzyme intermediate mimic produced by formate re-activation of a mutant endoglucanase lacking its catalytic nucleophile.
2001-04-01
Folding units in calcium vector protein of amphioxus: Structural and functional properties of its amino- and carboxy-terminal halves.
2001-04
Co-oximetry interference by hemoglobin-based blood substitutes.
2001-04
Ryanodine receptors/calcium release channels in heart failure and sudden cardiac death.
2001-04
Growth kinetics, diffraction properties and effect of agarose on the stability of a novel crystal form of Thermus thermophilus aspartyl-tRNA synthetase-1.
2001-04
Bicarbonate/lactate-based peritoneal dialysis solution increases cancer antigen 125 and decreases hyaluronic acid levels.
2001-04
Influence of particle size in the effect of polyethylene on human osteoblastic cells.
2001-04
SuperStar: improved knowledge-based interaction fields for protein binding sites.
2001-03-30
Expression of monocarboxylate transporter MCT1 in normal and neoplastic human CNS tissues.
2001-03-26
Blockade of lactate transport exacerbates delayed neuronal damage in a rat model of cerebral ischemia.
2001-03-23
Papillomavirus capsid protein expression in Escherichia coli: purification and assembly of HPV11 and HPV16 L1.
2001-03-16
The hydH/G Genes from Escherichia coli code for a zinc and lead responsive two-component regulatory system.
2001-03-16
Extracellular carbonic anhydrase activity facilitates lactic acid transport in rat skeletal muscle fibres.
2001-03-15
NAD/NADH models with axial/central chiralities: superiority of the quinoline ring system.
2001-03-09
Topology of the Na(+)/dicarboxylate cotransporter: the N-terminus and hydrophilic loop 4 are located intracellularly.
2001-03-09
Unusually short distances between the carbonyl oxygen and the tin atom in RCOSMR'3 (M = Ge, Sn, Pb): the importance of intramolecular n(O) --> sigma*(MS) orbital interactions.
2001-03-08
Quantitation of itraconazole in rat heparinized plasma by liquid chromatography-mass spectrometry.
2001-03-05
Conserved amino acids near the carboxy terminus of bacterial tyrosyl-tRNA synthetase are involved in tRNA and Tyr-AMP binding.
2001-03-02
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.
2001-03-01
SCO-spondin, a glycoprotein of the subcommissural organ/Reissner's fiber complex: evidence of a potent activity on neuronal development in primary cell cultures.
2001-03-01
Serum crosslaps correlations with serum ICTP and urine DPD in hemodialyzed and peritoneally dialyzed patients.
2001-03
A novel type II cytokeratin, mK6irs, is expressed in the Huxley and Henle layers of the mouse inner root sheath.
2001-03
Ultrasonic irradiation of dichlorvos: decomposition mechanism.
2001-03
Molecular comparison of the dense granule proteins GRA6 and GRA7 of Neospora hughesi and Neospora caninum.
2001-03
Crystallization and preliminary X-ray crystallographic analysis of RNase HIII from Bacillus subtilis.
2001-03
Purification and crystallization of the human RXRalpha ligand-binding domain-9-cisRA complex.
2001-03
Structure of the M148Q mutant of rusticyanin at 1.5 A: a model for the copper site of stellacyanin.
2001-03
Three-dimensional structure of human follicle-stimulating hormone.
2001-03
Differential recovery of retinal function after mitochondrial inhibition by methanol intoxication.
2001-03
Synthesis, crystal structure, spectral studies, and catechol oxidase activity of trigonal bipyramidal Cu(II) complexes derived from a tetradentate diamide bisbenzimidazole ligand.
2001-02-26
Laboratory study on the high-temperature capture of HCl gas by dry-injection of calcium-based sorbents.
2001-02-24
Formate species in the low-temperature oxidation of dimethyl ether.
2001-02-24
Exchange coupling in carboxylato-bridged dinuclear copper(II) compounds: a density functional study.
2001-02-02
A comparison of salts for the crystallization of macromolecules.
2001-02
Nonaqueous capillary electrophoresis-mass spectrometry for separation of venlafaxine and its phase I metabolites.
2001-02
Synthesis and biological evaluation of 2-(3'-(1H-tetrazol-5-yl) bicyclo[1.1.1]pent-1-yl)glycine (S-TBPG), a novel mGlu1 receptor antagonist.
2001-02
Conformational preferences of heterochiral peptides. Crystal structures of heterochiral peptides Boc-(D) Val-(D) Ala-Leu-Ala-OMe and Boc-Val-Ala-Leu-(D) Ala-OMe--enhanced stability of beta-sheet through C-H...O hydrogen bonds.
2001-02
Papain does not cleave operator-bound lambda repressor: structural characterization of the carboxy terminal domain and the hinge.
2001-02
[Radiolytic oxidation of tamoxifen with the free radicals OH- and/or HO2-].
2001-02
Alternative splicing and sequence diversity of transcripts from the oncosphere stage of Taenia solium with homology to the 45W antigen of Taenia ovis.
2001-02
The Streptomyces venezuelae pikAV gene contains a transcription unit essential for expression of enzymes involved in glycosylation of narbonolide and 10-deoxymethynolide.
2001-01-24
Solution structure and backbone dynamics of the DNA-binding domain of mouse Sox-5.
2001-01
The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro.
2001-01
Biodegradation of ethyl t-butyl ether (ETBE), methyl t-butyl ether (MTBE) and t-amyl methyl ether (TAME) by Gordonia terrae.
2001-01
Patents

Sample Use Guides

Fifty patients received 85% formic acid application using a topical application/needle puncture technique every other day.
Route of Administration: Topical
The adapted Aureobasidium pullulans strain could grow under the stress of 0.5 g/L furfural, 3 g/L HMF, 2g/L acetic acid, and 0.5 g/L formic acid, whereas the wild type did not.
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:48:03 GMT 2025
Edited
by admin
on Mon Mar 31 17:48:03 GMT 2025
Record UNII
3801F9644E
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMMONIUM FORMATE
HSDB   MI  
Systematic Name English
AMMONIUM FORMATE [HSDB]
Preferred Name English
AMMONIUM FORMATE [MI]
Common Name English
FORMIC ACID, AMMONIUM SALT
Common Name English
FORMATE, AMMONIUM
Common Name English
FORMIC ACID, AMMONIUM SALT (1:1)
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID6029624
Created by admin on Mon Mar 31 17:48:03 GMT 2025 , Edited by admin on Mon Mar 31 17:48:03 GMT 2025
PRIMARY
CAS
540-69-2
Created by admin on Mon Mar 31 17:48:03 GMT 2025 , Edited by admin on Mon Mar 31 17:48:03 GMT 2025
PRIMARY
WIKIPEDIA
AMMONIUM FORMATE
Created by admin on Mon Mar 31 17:48:03 GMT 2025 , Edited by admin on Mon Mar 31 17:48:03 GMT 2025
PRIMARY
PUBCHEM
10904
Created by admin on Mon Mar 31 17:48:03 GMT 2025 , Edited by admin on Mon Mar 31 17:48:03 GMT 2025
PRIMARY
FDA UNII
3801F9644E
Created by admin on Mon Mar 31 17:48:03 GMT 2025 , Edited by admin on Mon Mar 31 17:48:03 GMT 2025
PRIMARY
CHEBI
63050
Created by admin on Mon Mar 31 17:48:03 GMT 2025 , Edited by admin on Mon Mar 31 17:48:03 GMT 2025
PRIMARY
ECHA (EC/EINECS)
208-753-9
Created by admin on Mon Mar 31 17:48:03 GMT 2025 , Edited by admin on Mon Mar 31 17:48:03 GMT 2025
PRIMARY
HSDB
479
Created by admin on Mon Mar 31 17:48:03 GMT 2025 , Edited by admin on Mon Mar 31 17:48:03 GMT 2025
PRIMARY
MERCK INDEX
m1790
Created by admin on Mon Mar 31 17:48:03 GMT 2025 , Edited by admin on Mon Mar 31 17:48:03 GMT 2025
PRIMARY Merck Index
Related Record Type Details
PARENT -> SALT/SOLVATE