U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Details

Stereochemistry ACHIRAL
Molecular Formula C18H22N2
Molecular Weight 266.3807
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SIFAPRAZINE

SMILES

CN1CCN(CC1)C2=CC=CC=C2CC3=CC=CC=C3

InChI

InChIKey=SDJWUEKTZZQYLK-UHFFFAOYSA-N
InChI=1S/C18H22N2/c1-19-11-13-20(14-12-19)18-10-6-5-9-17(18)15-16-7-3-2-4-8-16/h2-10H,11-15H2,1H3

HIDE SMILES / InChI

Molecular Formula C18H22N2
Molecular Weight 266.3807
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Sifaprazine [FI 4303] is a substituted arylpiperazine with a similar structure to mianserin. Sifaprazine was undergoing preclinical evaluation with Ferrer in Spain as a potential antidepressant. However, no recent development has been reported.

Originator

Approval Year

Substance Class Chemical
Record UNII
372MWC170E
Record Status Validated (UNII)
Record Version