Velaprumig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 12:37:04 GMT 2025` Edited by `admin` on `Wed Apr 02 12:37:04 GMT 2025`
Protein Type	FC FUSION PROTEIN
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	36J438MZ7Z
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

483) [scFvkh anti-CD40LG (1-245) [V-KAPPA Musmus/Homsap (Mus musculus IGKV3-7*01 (87.9%) -IGKJ1*02 (100%)/Homo sapiens IGKV3-11*01 (75.5%) -IGKJ4*01 (90.9%) V124>L (108), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1-112) -15-mer tris(tetraglycyl-seryl) lin

Preferred Name

English

Velaprumig

Official Name

English

velaprumig [INN]

Common Name

English

Immunoglobulin G1, anti-(human CD40 ligand) (human-Mus musculus monoclonal hu5C8 single-chain variable fragment VL-(GGGGS)3-VH) fusion protein with peptide linker ((GGGGS)3) fusion protein with immunoglobulin G1, Fab fragment [140-glutamic acid, 223-seri

Common Name

English

immunoglobulin scFvkh-L-VH-G1(CH1-h)_scFvkh-L-kappa, anti-[Homo sapiens CD40LG (CD40 ligand, CD40L, tumor necrosis factor ligand superfamily member 5, TNFSF5, tumor necrosis factor related activation protein, TRAP, CD154)] and anti-[Homo sapiens ALB (alb

Common Name

English

Code System Code Type Description

INN

13342

Created by admin on Wed Apr 02 12:37:04 GMT 2025 , Edited by admin on Wed Apr 02 12:37:04 GMT 2025

PRIMARY

FDA UNII

36J438MZ7Z

Created by admin on Wed Apr 02 12:37:04 GMT 2025 , Edited by admin on Wed Apr 02 12:37:04 GMT 2025

PRIMARY

CAS

2988741-17-7

Created by admin on Wed Apr 02 12:37:04 GMT 2025 , Edited by admin on Wed Apr 02 12:37:04 GMT 2025

PRIMARY

From	To
2_398	2_458
2_286	2_351
2_149	2_223
2_23	2_92
1_407	1_463
1_282	1_356
1_149	1_223
1_23	1_92

Related Record Type Details


					ZIF514RVZR

ALBUMIN HUMAN

TARGET->LIGAND

Amount:


					61K7S69229

HUMAN CD40 LIGAND

TARGET->LIGAND

Interaction Type:

PRECLINICAL

Amount:

Related Record Type Details


					36J438MZ7Z

Velaprumig

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL