TECHNETIUM TC-99M MERTIATIDE

First approved in 1973

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H8N3O5S.2Na.O.Tc
Molecular Weight	418.21
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	-5

SHOW SMILES / InChI

Structure of TECHNETIUM TC-99M MERTIATIDE

Structure Search

SMILES

[O--].[Na+].[Na+].[Tc].[O-]C(=O)C[N-]C(=O)C[N-]C(=O)C[N-]C(=O)C[S-]

InChI

InChIKey=QKMHWHODQAOUFV-UHFFFAOYSA-I

InChI=1S/C8H13N3O5S.2Na.O.Tc/c12-5(2-10-7(14)4-17)9-1-6(13)11-3-8(15)16;;;;/h1-4H2,(H5,9,10,11,12,13,14,15,16,17);;;;/q;2*+1;-2;/p-5

HIDE SMILES / InChI

Molecular Formula	HO
Molecular Weight	17.0073
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Tc
Molecular Weight	98.0
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C8H12N3O5S
Molecular Weight	262.263
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2578
bone problems 43 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8429	OSTEOLITE Approved Use Unknown Launch Date 1977
osteogenesis 43 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8429	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 1978

PubMed

Title	Date	PubMed
Future of low specific activity molybdenum-99/technetium-99m generator.	2012 Oct	22642420

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:17:03 GMT 2023` Edited by `admin` on `Fri Dec 15 16:17:03 GMT 2023`
Record UNII	36ITO9SKQJ
Record Status	`Validated (UNII)`
Record Version

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Related Record	Type

Name

Type

Language

TECHNETIUM TC-99M MERTIATIDE

Common Name

English

TECHNETIUM TC 99M MERTIATIDE [USAN]

Common Name

English

DISODIUM (N-(N-(N-(MERCAPTOACETYL)GLYCYL)GLYCYL)GLYCINATO(5-)-N,N',N'',S)-OXO((SUP 99M)TC)

Systematic Name

English

TECHNESCAN MAG3

Brand Name

English

TECHNETIUM TC 99M MERTIATIDE [MI]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000177914