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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H27NO4
Molecular Weight 345.4327
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BEVANTOLOL, (R)-

SMILES

COC1=CC=C(CCNC[C@@H](O)COC2=CC(C)=CC=C2)C=C1OC

InChI

InChIKey=HXLAFSUPPDYFEO-QGZVFWFLSA-N
InChI=1S/C20H27NO4/c1-15-5-4-6-18(11-15)25-14-17(22)13-21-10-9-16-7-8-19(23-2)20(12-16)24-3/h4-8,11-12,17,21-22H,9-10,13-14H2,1-3H3/t17-/m1/s1

HIDE SMILES / InChI

Molecular Formula C20H27NO4
Molecular Weight 345.4327
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Different changes of plasma membrane beta-adrenoceptors in rat heart after chronic administration of propranolol, atenolol and bevantolol.
2007-07-12
Determination of bevantolol in human plasma by high performance liquid chromatography using solid phase extraction technique.
2007-07
Determination of bevantolol enantiomers in human plasma by coupled achiral-chiral high performance-liquid chromatography.
2007-07
Chiral purity test of bevantolol by capillaryelectrophoresis and high performance liquid chromatography.
2006-09
Effect of beta-blocker therapy on myocardial perfusion defects in thallium-201 scintigraphy in patients with dilated cardiomyopathy.
2005
Atypical cardiostimulant beta-adrenoceptor in the rat heart: stereoselective antagonism by bupranolol but lack of effect by some bupranolol analogues.
2003-08
Effect of beta-blockers on insulin resistance in patients with dilated cardiomyopathy.
2003-08
Comparison of treatment effects of bevantolol and metoprolol on cardiac function and natriuretic peptides in patients with dilated cardiomyopathy.
2002-12
Use of thallium-201 myocardial scintigraphy for the prediction of the response to beta-blocker therapy in patients with dilated cardiomyopathy.
2002-12
Integrated acquisition of analytical and biopharmaceutical screening data for beta-adrenergic-drugs employing diversified macrocycle supported potentiometric detection in HPLC systems.
2002-08
The release of the substrate for xanthine oxidase in hypertensive patients was suppressed by angiotensin converting enzyme inhibitors and alpha1-blockers.
2001-03
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 23:27:33 GMT 2025
Edited
by admin
on Mon Mar 31 23:27:33 GMT 2025
Record UNII
34P43RW460
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BEVANTOLOL, (R)-
Common Name English
(+)-BEVANTOLOL
Preferred Name English
2-PROPANOL, 1-((2-(3,4-DIMETHOXYPHENYL)ETHYL)AMINO)-3-(3-METHYLPHENOXY)-, (2R)-
Systematic Name English
Code System Code Type Description
CAS
135531-40-7
Created by admin on Mon Mar 31 23:27:33 GMT 2025 , Edited by admin on Mon Mar 31 23:27:33 GMT 2025
PRIMARY
FDA UNII
34P43RW460
Created by admin on Mon Mar 31 23:27:33 GMT 2025 , Edited by admin on Mon Mar 31 23:27:33 GMT 2025
PRIMARY
PUBCHEM
36690919
Created by admin on Mon Mar 31 23:27:33 GMT 2025 , Edited by admin on Mon Mar 31 23:27:33 GMT 2025
PRIMARY
Related Record Type Details
RACEMATE -> ENANTIOMER