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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H27NO4
Molecular Weight 345.4334
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BEVANTOLOL, (R)-

SMILES

Cc1cccc(c1)OC[C@@]([H])(CNCCc2ccc(c(c2)OC)OC)O

InChI

InChIKey=HXLAFSUPPDYFEO-QGZVFWFLSA-N
InChI=1S/C20H27NO4/c1-15-5-4-6-18(11-15)25-14-17(22)13-21-10-9-16-7-8-19(23-2)20(12-16)24-3/h4-8,11-12,17,21-22H,9-10,13-14H2,1-3H3/t17-/m1/s1

HIDE SMILES / InChI

Molecular Formula C20H27NO4
Molecular Weight 345.4334
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
The release of the substrate for xanthine oxidase in hypertensive patients was suppressed by angiotensin converting enzyme inhibitors and alpha1-blockers.
2001 Mar
Integrated acquisition of analytical and biopharmaceutical screening data for beta-adrenergic-drugs employing diversified macrocycle supported potentiometric detection in HPLC systems.
2002 Aug
Comparison of treatment effects of bevantolol and metoprolol on cardiac function and natriuretic peptides in patients with dilated cardiomyopathy.
2002 Dec
Use of thallium-201 myocardial scintigraphy for the prediction of the response to beta-blocker therapy in patients with dilated cardiomyopathy.
2002 Dec
Atypical cardiostimulant beta-adrenoceptor in the rat heart: stereoselective antagonism by bupranolol but lack of effect by some bupranolol analogues.
2003 Aug
Effect of beta-blockers on insulin resistance in patients with dilated cardiomyopathy.
2003 Aug
Effect of beta-blocker therapy on myocardial perfusion defects in thallium-201 scintigraphy in patients with dilated cardiomyopathy.
2005
Chiral purity test of bevantolol by capillaryelectrophoresis and high performance liquid chromatography.
2006 Sep
Determination of bevantolol in human plasma by high performance liquid chromatography using solid phase extraction technique.
2007 Jul
Determination of bevantolol enantiomers in human plasma by coupled achiral-chiral high performance-liquid chromatography.
2007 Jul
Different changes of plasma membrane beta-adrenoceptors in rat heart after chronic administration of propranolol, atenolol and bevantolol.
2007 Jul 12
Patents
Substance Class Chemical
Created
by admin
on Sat Jun 26 11:29:24 UTC 2021
Edited
by admin
on Sat Jun 26 11:29:24 UTC 2021
Record UNII
34P43RW460
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BEVANTOLOL, (R)-
Common Name English
(+)-BEVANTOLOL
Common Name English
2-PROPANOL, 1-((2-(3,4-DIMETHOXYPHENYL)ETHYL)AMINO)-3-(3-METHYLPHENOXY)-, (2R)-
Systematic Name English
Code System Code Type Description
CAS
135531-40-7
Created by admin on Sat Jun 26 11:29:25 UTC 2021 , Edited by admin on Sat Jun 26 11:29:25 UTC 2021
PRIMARY
FDA UNII
34P43RW460
Created by admin on Sat Jun 26 11:29:25 UTC 2021 , Edited by admin on Sat Jun 26 11:29:25 UTC 2021
PRIMARY
PUBCHEM
36690919
Created by admin on Sat Jun 26 11:29:25 UTC 2021 , Edited by admin on Sat Jun 26 11:29:25 UTC 2021
PRIMARY
Related Record Type Details
RACEMATE -> ENANTIOMER