Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C17H18FN3S.2C4H4O4 |
| Molecular Weight | 547.553 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 2 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN1CCN2C(C1)CN=C(C3=CC=CS3)C4=C2C=C(F)C=C4
InChI
InChIKey=RZJUIBXCUCYJRN-SPIKMXEPSA-N
InChI=1S/C17H18FN3S.2C4H4O4/c1-20-6-7-21-13(11-20)10-19-17(16-3-2-8-22-16)14-5-4-12(18)9-15(14)21;2*5-3(6)1-2-4(7)8/h2-5,8-9,13H,6-7,10-11H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
| Molecular Formula | C4H4O4 |
| Molecular Weight | 116.0722 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Optical Activity | NONE |
| Molecular Formula | C17H18FN3S |
| Molecular Weight | 315.408 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Timelotem is a benzodiazepine derivative patented by Kali-Chemie Pharma G.m.b.H. as an anesthetic agent. In preclinical models, Timelotem shows atypical antipsychotic activity. Timelotem antagonizes DL-2-amino-5-phosphonovaleric acid (AP-5)-induced sniffing and the body turns in rats. Further, Timelotem antagonized amphetamine-induced stereotyped behavior in rats but was found less active than haloperidol in this test.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:44:40 GMT 2023
by
admin
on
Sat Dec 16 08:44:40 GMT 2023
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| Record UNII |
3474L59RX5
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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3474L59RX5
Created by
admin on Sat Dec 16 08:44:40 GMT 2023 , Edited by admin on Sat Dec 16 08:44:40 GMT 2023
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105566-70-9
Created by
admin on Sat Dec 16 08:44:40 GMT 2023 , Edited by admin on Sat Dec 16 08:44:40 GMT 2023
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6918060
Created by
admin on Sat Dec 16 08:44:40 GMT 2023 , Edited by admin on Sat Dec 16 08:44:40 GMT 2023
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PRIMARY |
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PARENT -> SALT/SOLVATE |
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ACTIVE MOIETY |