Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Tue Apr 01 18:55:30 GMT 2025
by
admin
on
Tue Apr 01 18:55:30 GMT 2025
|
| Protein Sub Type | |
| Sequence Type | COMPLETE |
| Record UNII |
3426PF4EST
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
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Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
O96013
Created by
admin on Tue Apr 01 18:55:30 GMT 2025 , Edited by admin on Tue Apr 01 18:55:30 GMT 2025
|
PRIMARY | |||
|
3426PF4EST
Created by
admin on Tue Apr 01 18:55:30 GMT 2025 , Edited by admin on Tue Apr 01 18:55:30 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
F-3758309 is antiproliferative and induces apoptosis in a HCT116 tumor model.
IC50
|
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| AMINO ACID SUBSTITUTION | [1_474] | DEXFOSFOSERINE | VI4F0K069V | |||
| AMINO ACID SUBSTITUTION | [1_41] [1_104] [1_148] [1_167] [1_181] [1_195] [1_258] [1_267] [1_291] | DEXFOSFOSERINE | VI4F0K069V | |||
| AMINO ACID SUBSTITUTION | [1_187] | THREONINE PHOSPHATE | 3L4WX7B1EI |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT | CHEMICAL |
|