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Details

Stereochemistry ACHIRAL
Molecular Formula Br.Rb
Molecular Weight 165.372
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RUBIDIUM BROMIDE

SMILES

[Br-].[Rb+]

InChI

InChIKey=JAAGVIUFBAHDMA-UHFFFAOYSA-M
InChI=1S/BrH.Rb/h1H;/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula Rb
Molecular Weight 85.4678
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula BrH
Molecular Weight 80.912
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/3311597 | https://www.ncbi.nlm.nih.gov/pubmed/26442267

Rubidium chloride is an inorganic compound with the formula RbCl. It appears to be nontoxic and therapeutically effective in several types of depressive disorders. This drug develops his action on dopaminergic stimulation reducing the depressive pattern. Also radioactive rubidium-82 chloride is used as diagnostic agent in positron emission tomography (PET).

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
RUBINORM

Approved Use

Depression
PubMed

PubMed

TitleDatePubMed
Brain norepinephrine: enhanced turnover after rubidium treatment.
1970 Apr 24
Rubidium chloride ingestion by volunteer subjects: initial experience.
1971
Effects of rubidium chloride on the course of manic-depressive illness.
1978 May
Nerve fibre refractory period in patients treated with rubidium and lithium.
1978 Sep
Exploration of the clinical profile of rubidium chloride in depression: a systematic open trial.
1988 Jun
Inhibition of HIV-1 infection by zinc group metal compounds.
1999 Sep
Gating properties of inward-rectifier potassium channels: effects of permeant ions.
2001 Nov 1
Patents

Sample Use Guides

540 mg/day
Route of Administration: Oral
In Vitro Use Guide
Rubidium chloride accelerated cAMP synthesis in rat brain cortex membranes. The effect was dose-dependent and yielded above 2-fold activation of adenylate cyclase. It has been shown that Rb+ influenced directly the catalytic subunit of the enzyme and did not substitute Mg2+ in formation of the metal-ATP complex in this reaction. The stimulatory effect of Rb+ was additive to the activation of adenylate cyclase by the half-maximal (0.3 microM) as well as by the saturating (10 microM) forskolin concentrations, pointing to the fact that these effectors activate different isoforms of the enzyme in rat brain cortex.
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:45:22 GMT 2023
Edited
by admin
on Sat Dec 16 08:45:22 GMT 2023
Record UNII
33CM31XVQQ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RUBIDIUM BROMIDE
MI  
Systematic Name English
RUBIDIUM BROMIDE (RBBR)
Systematic Name English
RUBIDIUM MONOBROMIDE
Systematic Name English
RUBIDIUM BROMIDE [MI]
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID00894885
Created by admin on Sat Dec 16 08:45:22 GMT 2023 , Edited by admin on Sat Dec 16 08:45:22 GMT 2023
PRIMARY
CAS
7789-39-1
Created by admin on Sat Dec 16 08:45:22 GMT 2023 , Edited by admin on Sat Dec 16 08:45:22 GMT 2023
PRIMARY
FDA UNII
33CM31XVQQ
Created by admin on Sat Dec 16 08:45:22 GMT 2023 , Edited by admin on Sat Dec 16 08:45:22 GMT 2023
PRIMARY
PUBCHEM
4670918
Created by admin on Sat Dec 16 08:45:22 GMT 2023 , Edited by admin on Sat Dec 16 08:45:22 GMT 2023
PRIMARY
WIKIPEDIA
RUBIDIUM BROMIDE
Created by admin on Sat Dec 16 08:45:22 GMT 2023 , Edited by admin on Sat Dec 16 08:45:22 GMT 2023
PRIMARY
MERCK INDEX
m9686
Created by admin on Sat Dec 16 08:45:22 GMT 2023 , Edited by admin on Sat Dec 16 08:45:22 GMT 2023
PRIMARY Merck Index
ECHA (EC/EINECS)
232-162-5
Created by admin on Sat Dec 16 08:45:22 GMT 2023 , Edited by admin on Sat Dec 16 08:45:22 GMT 2023
PRIMARY