U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 21:45:42 GMT 2025
Edited
by admin
on Mon Mar 31 21:45:42 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
333YMY788E
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OMP-59R5
Preferred Name English
TAREXTUMAB
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
Tarextumab [WHO-DD]
Common Name English
tarextumab [INN]
Common Name English
IMMUNOGLOBULIN G2, ANTI-(HUMAN NOTCH (RECEPTOR) NOTCH2/NOTCH (RECEPTOR) NOTCH3) (HUMAN OMP-59R5 HEAVY CHAIN), DISULFIDE WITH HUMAN OMP-59R5 LIGHT CHAIN, DIMER
Common Name English
TAREXTUMAB [USAN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 461314
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
FDA ORPHAN DRUG 461414
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
NCI_THESAURUS C20401
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
Code System Code Type Description
WIKIPEDIA
Tarextumab
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
PRIMARY
NCI_THESAURUS
C95719
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
PRIMARY
EVMPD
SUB185334
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
PRIMARY
FDA UNII
333YMY788E
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
PRIMARY
SMS_ID
100000171718
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
PRIMARY
ChEMBL
CHEMBL3301588
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
PRIMARY
USAN
BC-112
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
PRIMARY
INN
9762
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
PRIMARY
CAS
1359940-55-8
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
PRIMARY
DRUG BANK
DB12104
Created by admin on Mon Mar 31 21:45:42 GMT 2025 , Edited by admin on Mon Mar 31 21:45:42 GMT 2025
PRIMARY
From To
1_22 1_96
1_142 1_198
1_255 1_315
1_361 1_419
2_22 2_96
2_142 2_198
2_255 2_315
2_361 2_419
3_23 3_89
3_135 3_195
4_23 4_89
4_135 4_195
1_129 3_215
2_129 4_215
1_217 2_217
1_218 2_218
1_221 2_221
1_224 2_224
Glycosylation Link Type Site
N 1_291
N 2_291
Related Record Type Details
NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2
TARGET -> INHIBITOR
NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 3 (HUMAN)
TARGET -> INHIBITOR
Related Record Type Details
TAREXTUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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National Center for Advancing Translational Sciences (NCATS),
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