U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 09:41:36 GMT 2023
Edited
by admin
on Sat Dec 16 09:41:36 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
3318TFY23Q
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A9
Common Name English
UDP-GLUCURONOSYLTRANSFERASE 1A9
Common Name English
UDP-GLUCURONOSYLTRANSFERASE 1-9
Common Name English
UGT1A9
Common Name English
UGT-1A9
Common Name English
Code System Code Type Description
FDA UNII
3318TFY23Q
Created by admin on Sat Dec 16 09:41:38 GMT 2023 , Edited by admin on Sat Dec 16 09:41:38 GMT 2023
PRIMARY
WIKIPEDIA
UGT1A9
Created by admin on Sat Dec 16 09:41:38 GMT 2023 , Edited by admin on Sat Dec 16 09:41:38 GMT 2023
PRIMARY
CAS
400706-57-2
Created by admin on Sat Dec 16 09:41:38 GMT 2023 , Edited by admin on Sat Dec 16 09:41:38 GMT 2023
PRIMARY
UNIPROT
O60656
Created by admin on Sat Dec 16 09:41:38 GMT 2023 , Edited by admin on Sat Dec 16 09:41:38 GMT 2023
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_46
N 1_267
N 1_319
Related Record Type Details
SUBSTRATE -> METABOLIC ENZYME
MINOR
SUBSTRATE -> METABOLIC ENZYME
MINOR
SUBSTRATE -> METABOLIC ENZYME
MAJOR
SUBSTRATE -> METABOLIC ENZYME
MAJOR
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
Glasdegib is metabolized primarily by the CYP3A4 pathway, with minor contributions by CYP2C8 and UGT1A9
MINOR
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
MINOR
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
MINOR
SUBSTRATE -> METABOLIC ENZYME
MINOR
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
MAJOR
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
MAJOR
SUBSTRATE -> METABOLIC ENZYME
IN-VITRO
Km
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
Inhibits at clinically relevant concentrations.
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
MINOR
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
IN VITRO
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
MAJOR
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
MAJOR
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED) CHEMICAL