Approval Year
Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 09:41:36 GMT 2023
by
admin
on
Sat Dec 16 09:41:36 GMT 2023
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Protein Sub Type | |
Sequence Type | COMPLETE |
Record UNII |
3318TFY23Q
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Record Status |
Validated (UNII)
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Record Version |
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-
Download
Name | Type | Language | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
Code System | Code | Type | Description | ||
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3318TFY23Q
Created by
admin on Sat Dec 16 09:41:38 GMT 2023 , Edited by admin on Sat Dec 16 09:41:38 GMT 2023
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PRIMARY | |||
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UGT1A9
Created by
admin on Sat Dec 16 09:41:38 GMT 2023 , Edited by admin on Sat Dec 16 09:41:38 GMT 2023
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PRIMARY | |||
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400706-57-2
Created by
admin on Sat Dec 16 09:41:38 GMT 2023 , Edited by admin on Sat Dec 16 09:41:38 GMT 2023
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PRIMARY | |||
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O60656
Created by
admin on Sat Dec 16 09:41:38 GMT 2023 , Edited by admin on Sat Dec 16 09:41:38 GMT 2023
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PRIMARY |
Glycosylation Type | HUMAN |
Glycosylation Link Type | Site |
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N | 1_46 |
N | 1_267 |
N | 1_319 |
Related Record | Type | Details | ||
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SUBSTRATE -> METABOLIC ENZYME |
MINOR
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SUBSTRATE -> METABOLIC ENZYME |
MINOR
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME |
Glasdegib is metabolized primarily by the CYP3A4 pathway, with minor contributions by CYP2C8 and UGT1A9
MINOR
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME |
MINOR
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE -> METABOLIC ENZYME |
MINOR
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SUBSTRATE -> METABOLIC ENZYME |
MINOR
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME |
MAJOR
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SUBSTRATE -> METABOLIC ENZYME |
IN-VITRO
Km
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE -> METABOLIC ENZYME |
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INHIBITOR -> METABOLIC ENZYME |
Inhibits at clinically relevant concentrations.
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME |
MINOR
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME |
IN VITRO
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME |
MAJOR
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE -> METABOLIC ENZYME | |||
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SUBSTRATE -> METABOLIC ENZYME |
MAJOR
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Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
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MOL_WEIGHT:NUMBER AVERAGE(CALCULATED) | CHEMICAL |
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