GARADACIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:08:23 GMT 2023` Edited by `admin` on `Sat Dec 16 15:08:23 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	32W6AJL0DY
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GARADACIMAB

Official Name

English

Garadacimab [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G4, ANTI-(HUMAN BLOOD-COAGULATION FACTOR XIIA) (HUMAN MONOCLONAL CSL312 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL CSL312 .LAMBDA.-CHAIN, DIMER

Common Name

English

CSL312 (ANTI-FXIIA MONOCLONAL ANTIBODY)

Common Name

English

CSL-312

Common Name

English

garadacimab [INN]

Common Name

English

IMMUNOGLOBULIN G4-LAMBDA, ANTI-(HOMO SAPIENS F12 (COAGULATION FACTOR XII, HAGEMAN FACTOR) ACTIVATED (F12A, FXIIA)), MONOCLONAL ANTIBODY

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

715419

Created by admin on Sat Dec 16 15:08:23 GMT 2023 , Edited by admin on Sat Dec 16 15:08:23 GMT 2023

FDA ORPHAN DRUG

870622

Created by admin on Sat Dec 16 15:08:23 GMT 2023 , Edited by admin on Sat Dec 16 15:08:23 GMT 2023

Code System Code Type Description

FDA UNII

32W6AJL0DY

Created by admin on Sat Dec 16 15:08:23 GMT 2023 , Edited by admin on Sat Dec 16 15:08:23 GMT 2023

PRIMARY

DRUG BANK

DB15629

Created by admin on Sat Dec 16 15:08:23 GMT 2023 , Edited by admin on Sat Dec 16 15:08:23 GMT 2023

PRIMARY

NCI_THESAURUS

C166633

Created by admin on Sat Dec 16 15:08:23 GMT 2023 , Edited by admin on Sat Dec 16 15:08:23 GMT 2023

PRIMARY

CAS

2162134-62-3

Created by admin on Sat Dec 16 15:08:23 GMT 2023 , Edited by admin on Sat Dec 16 15:08:23 GMT 2023

PRIMARY

INN

10996

Created by admin on Sat Dec 16 15:08:23 GMT 2023 , Edited by admin on Sat Dec 16 15:08:23 GMT 2023

PRIMARY

From	To
1_22	1_96
1_156	1_212
1_143	3_214
1_235	2_235
1_238	2_238
1_270	1_330
1_376	1_434
2_22	2_96
2_156	2_212
2_270	2_330
2_376	2_434
2_143	4_214
3_22	3_89
3_137	3_196
4_22	4_89
4_137	4_196

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_306
N	2_306

Related Record Type Details


					QB9PBS8MOK

COAGULATION FACTOR XIIA

TARGET -> INHIBITOR

Related Record Type Details


					32W6AJL0DY

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL