Resecabtagene autoleucel transgene insert

Substance Class	Nucleic Acid Created by `admin` on `Wed Apr 02 20:20:58 GMT 2025` Edited by `admin` on `Wed Apr 02 20:20:58 GMT 2025`
Nucleic Acid Type	VECTOR
Sequence Origin	VIRAL, HUMAN
Sequence Type	COMPLETE
Record UNII	32QJS39Y9P
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

Common Name

English

Resecabtagene autoleucel transgene insert encoding a chimeric antigen receptor (CAR) targeting CD19

Preferred Name

English

Code System Code Type Description

FDA UNII

32QJS39Y9P

Created by admin on Wed Apr 02 20:20:58 GMT 2025 , Edited by admin on Wed Apr 02 20:20:58 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_1-1_5243	5243 / 5243

Linkage	Site Range	Site Count
Phosphate	1_2-1_5243	5242 / 5242

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
self-inactivating (Sin) LTR region (delta-U3)	NUCLEIC ACID FEATURE

R and U5 components of HIV-1 LTR	NUCLEIC ACID FEATURE

WPRE no X	NUCLEIC ACID FEATURE

Truncated gag	NUCLEIC ACID FEATURE

HIV-1 Psi	NUCLEIC ACID FEATURE

CAR targeting CD19	NUCLEIC ACID FEATURE

Rev response element (RRE), splice acceptor (SA) site 7	NUCLEIC ACID FEATURE

central polypurine tract (cPPT) and termination squence (CTS)	NUCLEIC ACID FEATURE

5' terminal R and U5 components of human immunodeficiency virus 1 (HIV-1) long terminal repeat (LTR) region	NUCLEIC ACID FEATURE

Essential lentiviral backbone element	NUCLEIC ACID FEATURE

Essential lentiviral backbone element	NUCLEIC ACID FEATURE

EF1alpha promoter	NUCLEIC ACID FEATURE