Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H15Cl2NO2 |
| Molecular Weight | 276.159 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CC1=CC=C(C=C1)N(CCCl)CCCl
InChI
InChIKey=RQAFMLCWWGDNLI-UHFFFAOYSA-N
InChI=1S/C12H15Cl2NO2/c13-5-7-15(8-6-14)11-3-1-10(2-4-11)9-12(16)17/h1-4H,5-9H2,(H,16,17)
| Molecular Formula | C12H15Cl2NO2 |
| Molecular Weight | 276.159 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The allylic 7-ketone at the steroidal skeleton is crucial for the antileukemic potency of chlorambucil's active metabolite steroidal esters. | 2004 Nov |
|
| [Cytotoxic steroids with antiestrogenic activity of the 11alpha-acyloxyestra-1,3,5(10)-triene series]. | 2006 Mar-Apr |
|
| Aneugenic potential of the nitrogen mustard analogues melphalan, chlorambucil and p-N,N-bis(2-chloroethyl)aminophenylacetic acid in cell cultures in vitro. | 2007 Apr 1 |
|
| Cytogenetic and antineoplastic effects of modified steroidal alkylators. | 2010 Feb |
|
| Fluorescence in situ hybridization in combination with the comet assay and micronucleus test in genetic toxicology. | 2010 Sep 15 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Tue Oct 22 14:17:53 UTC 2019
by
admin
on
Tue Oct 22 14:17:53 UTC 2019
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| Record UNII |
32842A3UZP
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| Record Status |
Validated (UNII)
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| Record Version |
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10477-72-2
Created by
admin on Tue Oct 22 14:17:53 UTC 2019 , Edited by admin on Tue Oct 22 14:17:53 UTC 2019
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10477-72-2
Created by
admin on Tue Oct 22 14:17:53 UTC 2019 , Edited by admin on Tue Oct 22 14:17:53 UTC 2019
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25306
Created by
admin on Tue Oct 22 14:17:53 UTC 2019 , Edited by admin on Tue Oct 22 14:17:53 UTC 2019
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> METABOLITE ACTIVE |
Has antineoplastic activity
|
