1,4-DITHIANE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H8S2
Molecular Weight	120.236
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C1CSCCS1

InChI

InChIKey=LOZWAPSEEHRYPG-UHFFFAOYSA-N

InChI=1S/C4H8S2/c1-2-6-4-3-5-1/h1-4H2

HIDE SMILES / InChI

Molecular Formula	C4H8S2
Molecular Weight	120.236
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Michael Elliott's billion dollar crystals and other discoveries in insecticide chemistry.	2010-11	20552666
Total synthesis of (+)-ambruticin S: probing the pharmacophoric subunit.	2010-08-20	20704433
Cell-selective, apoptosis-inducing rhodium(III) crown thiaether complexes.	2010-07-05	20572280
Synthesis of the bis-spiroacetal C25-C40 moiety of the antimitotic agent spirastrellolide B using a bis-dithiane deprotection/spiroacetalisation sequence.	2010-06-14	20445924
Aqabamycins A-G: novel nitro maleimides from a marine Vibrio species. I. Taxonomy, fermentation, isolation and biological activities.	2010-06	20431617
Aqabamycins A-G: novel nitro maleimides from a marine Vibrio species: II. Structure elucidation.	2010-06	20431615
Novel Cr(III) dinuclear complexes supported by salicyloylhydrazono dithiolane and dithiane ligands: synthesis, stability, crystal structures and magnetic properties.	2010-05-21	20386789
2-[4-Chloro-3-(4-ethoxy-benz-yl)phen-yl]-1,3-dithiane.	2010-05-19	21579467
Headspace-trap gas chromatography-mass spectrometry for determination of sulphur mustard and related compounds in soil.	2010-04-02	20189185
1,3-Dithian-2-one azine.	2010-03-27	21580759
Towards the second generation of Boceprevir: Dithianes as an alternative P2 substituent for 2,2-dimethyl cycloproyl proline in HCV NS3 protease inhibitors.	2010-03-01	20149655
Trace determination of sulphur mustard and related compounds in water by headspace-trap gas chromatography-mass spectrometry.	2010-01-29	20015497
Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C.	2010-01-21	20161975
Improved method for the synthesis of beta-carbonyl silyl-1,3-dithianes by the double conjugate addition of 1,3-dithiol to propargylic carbonyl compounds.	2009-12-04	19877611
Solid-phase organic synthesis of difluoroalkyl entities using a novel fluorinating cleavage strategy: part 2. Synthesis of three small gem-difluorinated compound libraries using a dithiane linker.	2009-09-03	19722501
(+)-Rimocidin synthetic studies: construction of the C(1-27) aglycone skeleton.	2009-08-21	19621880
2-(Pyrene-1-yl)-1,3-dithiane.	2009-03-28	21582599
Ring-opening reaction of Bus- and SES-protected aziridines using lithiated dithianes.	2009-02-07	19156316
7-Nitro-1,2,3,4-tetra-hydro-naphthalene-1-spiro-2'-(1,3-dithiane).	2009-01-17	21581948
Kinetics of the gas-phase reactions of OH and NO3 radicals and O3 with 1,4-thioxane and 1,4-dithiane.	2008-12-25	19093823
Total synthesis of (-)-2-epi-peloruside A.	2008-12-18	19007239
Evolution of multi-component anion relay chemistry (ARC): construction of architecturally complex natural and unnatural products.	2008-12-07	19030533
Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease.	2008-10-22	18945348
Total syntheses of (+)- and (-)-peribysin E.	2008-10-15	18783227
A chiron approach to the total synthesis of (+)-aculeatin D.	2008-09-19	18707170
Synthesis and evaluation of the cytotoxicity of apoptolidinones A and D.	2008-07-04	18543990
Synthesis of 5-hydroxy-2,3,4,5-tetrahydro-[1H]-2-benzazepin-4-ones: selective antagonists of muscarinic (M3) receptors.	2008-06-21	18528576
Influence of the core conformation on the NH-tautomerism in porphyrins: a study of meso-(1,3-dithian-2-yl)porphyrins.	2008-03-21	18288865
2-(1,3-Dithian-2-yl-idene)-1-phenyl-butane-1,3-dione.	2008-01-30	21201553
2,6,7-trithiabicyclo[2.2.2]octanes as promising photolabile tags for combinatorial encoding.	2008-01-04	18069853
Total synthesis of (+)-tedanolide.	2007-09-05	17691787
The spirastrellolides: construction of the southern C(1)-C(25) fragment exploiting anion relay chemistry.	2007-08-16	17637031
Conformational landscape of meso-(1,3-dithian-2-yl)porphyrins.	2007-08-03	17628109
Selectivity among organic sulfur compounds in one- and two-liquid-phase cultures of Rhodococcus sp. strain JVH1.	2007-08	17091345
Photoactive barbiturate receptors: an ultimate lock-and-key system in which the key unlocks the lock.	2007-03-15	17291004
Synthesis and use of deuterated palmitic acids to decipher the cryptoregiochemistry of a Delta13 desaturation.	2007-02-02	17253792
Targeting human immunodeficiency virus type 1 assembly, maturation and budding.	2007	21901072
The nature of the chemical bond in linear three-body systems: from i3- to mixed chalcogen/halogen and trichalcogen moieties.	2007	18389065
Photoamplification and multiple tag release in a linear peptide-based array of dithiane adducts.	2007	17628471
Effect of 2,6-disubstituted aryl groups on acyclic conformation: preference for an antiperiplanar orientation of the geminal and vicinal hydrogens.	2006-11-10	17081013
Enantioselective formal total synthesis of the antitumor macrolide bryostatin 7.	2006-09-28	16986929
Second-generation total synthesis of azaspiracids-1, -2, and -3.	2006-07-17	17441061
When ethyl is infinitely different from methyl: double addition of lithiated dithianes to aromatic carboxylates revisited.	2006-06-23	16776546
Stereocontrolled and convergent total synthesis of amphidinolide T3.	2006-06-09	16749797
Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3.	2006-04-10	16548033
Molecular characterization of the HIV-1 gag nucleocapsid gene associated with vertical transmission.	2006-04-06	16600029
Calorimetric and computational study of 1,4-dithiacyclohexane 1,1-dioxide (1,4-dithiane sulfone).	2006-03-31	16555808
Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1.	2006-03-08	16506764
Anion relay chemistry: an effective tactic for diversity oriented synthesis.	2006-01-11	16390124
Reactions Between Chalcogen Donors and Dihalogens/Interalogens: Typology of Products and Their Characterization by FT-Raman Spectroscopy.	2006	17497008

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:06:09 GMT 2025` Edited by `admin` on `Mon Mar 31 19:06:09 GMT 2025`
Record UNII	3274B1T5A0
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FEMA NO. 3831

Preferred Name

English

1,4-DITHIANE

Systematic Name

English

1,4-DITHIANE [FHFI]

Common Name

English

NSC-24178

Code

English

1,4-DITHIANE [HSDB]

Common Name

English

P-DITHANE

Common Name

English

DIETHYLENE DISULFIDE

Common Name

English

P-DITHIANE

Common Name

English

1,4-DITHIACYCLOHEXANE

Systematic Name

English

Classification Tree Code System Code

JECFA EVALUATION

1,4-DITHIANE