TRIMETOZINE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H19NO5
Molecular Weight	281.3044
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC(=CC(OC)=C1OC)C(=O)N2CCOCC2

InChI

InChIKey=XWVOEFLBOSSYGM-UHFFFAOYSA-N

InChI=1S/C14H19NO5/c1-17-11-8-10(9-12(18-2)13(11)19-3)14(16)15-4-6-20-7-5-15/h8-9H,4-7H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C14H19NO5
Molecular Weight	281.3044
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4871781 | https://www.ncbi.nlm.nih.gov/pubmed/4600840

Trimetozine (brand name Trioxazine) is a sedative agent, which has been used in the treatment of anxiety.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Anxiety 275 Sources: https://www.ncbi.nlm.nih.gov/pubmed/4600840	Primary		Not Provided 511	trioxazine Approved Use Unknown

PubMed

Title	Date	PubMed
[Effects of tranquilizing agents on bioelectrical activity of the rat brain].	1992-06	1359909
Simultaneous determination of glucuronides of trimetozine in human urine by gas chromatography.	1982-09-10	7130313
[Behavioral and neuropharmacological studies of trioxazin (trimetozine) (author's transl)].	1978-08	34972
Trioxazine; its history and therapeutic use.	1973	4600840
[Trimetozine in hospital geriatrics].	1967-03-05	5614940
Clinical observations concerning the effect of trioxazine, a tranquillizer.	1960	13871648

Patents

Sample Use Guides

In Vivo Use Guide

1200 mg tablet

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:51:40 GMT 2025` Edited by `admin` on `Mon Mar 31 17:51:40 GMT 2025`
Record UNII	31EPT7G9PL
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ABBOTT-22370

Preferred Name

English

TRIMETOZINE

Official Name

English

TRIMETOZINE [MI]

Common Name

English

METHANONE, 4-MORPHOLINYL(3,4,5-TRIMETHOXYPHENYL)-

Systematic Name

English

PS 2383

Code

English

PS-2383

Code

English

TRIMETOZINE [MART.]

Common Name

English

NSC-62939

Code

English

TRIMETOZINE [USAN]

Common Name

English

trimetozine [INN]

Common Name

English

Trimetozine [WHO-DD]

Common Name

English

MORPHOLINE, 4-(3,4,5-TRIMETHOXYBENZOYL)-

Systematic Name

English

4-(3,4,5-Trimethoxybenzoyl)morpholine

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28197