U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:34:46 GMT 2023
Edited
by admin
on Sat Dec 16 14:34:46 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
30WLL6DR9O
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Vonsetamig
INN  
Official Name English
vonsetamig [INN]
Common Name English
Immunoglobulin G4-kappa, anti-[Homo sapiens TNFRSF17 (TNF receptor superfamily member 17, BCMA, TNFRSF13A, CD269) and CD3E (CD3 epsilon)], Homo sapiens monoclonal antibody, bispecific, bivalent
Common Name English
Immunoglobulin G4 [103-cysteine,108-cysteine,233-proline,238-proline,239-valine,240-alanine,de-241-glycine], anti-(human B-cell maturation antigen) (human monoclonal REGN5459 γ4-chain), disulfide with human monoclonal REGN5459 κ-chain, (231→230′),(
Common Name English
Code System Code Type Description
NCI_THESAURUS
C199130
Created by admin on Sat Dec 16 14:34:47 GMT 2023 , Edited by admin on Sat Dec 16 14:34:47 GMT 2023
PRIMARY
FDA UNII
30WLL6DR9O
Created by admin on Sat Dec 16 14:34:47 GMT 2023 , Edited by admin on Sat Dec 16 14:34:47 GMT 2023
PRIMARY
INN
12494
Created by admin on Sat Dec 16 14:34:47 GMT 2023 , Edited by admin on Sat Dec 16 14:34:47 GMT 2023
PRIMARY
CAS
2408319-33-3
Created by admin on Sat Dec 16 14:34:46 GMT 2023 , Edited by admin on Sat Dec 16 14:34:46 GMT 2023
PRIMARY
From To
1_22 1_96
1_103 1_108
1_139 3_215
1_152 1_208
1_231 2_230
1_234 2_233
1_265 1_325
1_371 1_429
2_22 2_96
2_138 4_215
2_151 2_207
2_264 2_324
2_370 2_428
3_23 3_88
3_135 3_195
4_23 4_88
4_135 4_195
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_301
N 2_300
Related Record Type Details
TARGET -> ACTIVATOR
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL