URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A4

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 11:14:03 UTC 2023` Edited by `admin` on `Sat Dec 16 11:14:03 UTC 2023`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	2Z7LDE78YX
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A4

Common Name

English

UGT1A4

Common Name

English

UDP-GLUCURONOSYLTRANSFERASE 1-4

Common Name

English

UGT-1A4

Common Name

English

UDP-GLUCURONOSYLTRANSFERASE 1A4

Common Name

English

Code System Code Type Description

CAS

400706-61-8

Created by admin on Sat Dec 16 11:14:05 UTC 2023 , Edited by admin on Sat Dec 16 11:14:05 UTC 2023

PRIMARY

UNIPROT

P22310

Created by admin on Sat Dec 16 11:14:05 UTC 2023 , Edited by admin on Sat Dec 16 11:14:05 UTC 2023

PRIMARY

WIKIPEDIA

UGT1A4

Created by admin on Sat Dec 16 11:14:05 UTC 2023 , Edited by admin on Sat Dec 16 11:14:05 UTC 2023

PRIMARY

FDA UNII

2Z7LDE78YX

Created by admin on Sat Dec 16 11:14:05 UTC 2023 , Edited by admin on Sat Dec 16 11:14:05 UTC 2023

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_91
N	1_114
N	1_268
N	1_320

Related Record Type Details


					JKZ19V908O

ASENAPINE

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MAJOR


					Y5L2157C4J

TACROLIMUS ANHYDROUS

SUBSTRATE -> METABOLIC ENZYME

Amount:


					WX8LOM674D

NELONICLINE

SUBSTRATE -> METABOLIC ENZYME

Comments:

100% conversion to M1

Interaction Type:

MAJOR


					6C282481IP

Ertugliflozin

INHIBITOR -> METABOLIC ENZYME


					19P708E787

SARPOGRELATE

SUBSTRATE -> METABOLIC ENZYME


					6783M2LV5X

PEXIDARTINIB

SUBSTRATE -> METABOLIC ENZYME

Amount:


					12G01I6BBU

EZOGABINE

SUBSTRATE -> METABOLIC ENZYME

Amount:


					R60L0SM5BC

MIDAZOLAM

SUBSTRATE -> METABOLIC ENZYME

Amount:


					1806D8D52K

AMITRIPTYLINE

SUBSTRATE -> METABOLIC ENZYME


					OSP71S83EU

LORLATINIB

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MAJOR


					S798V6YJRP

EDARAVONE

SUBSTRATE -> METABOLIC ENZYME


					NQU9IPY4K9

CEDIRANIB

SUBSTRATE -> METABOLIC ENZYME


					F925RR824R

TECOVIRIMAT

SUBSTRATE -> METABOLIC ENZYME

Amount:


					5S371K6132

RIVOCERANIB

SUBSTRATE -> METABOLIC ENZYME

Amount:


					70BSQ12069

LUMATEPERONE

SUBSTRATE -> METABOLIC ENZYME


					YG57I8T5M0

IDELALISIB

SUBSTRATE -> METABOLIC ENZYME


					8JYO8VTR11

BMS-823778 FREE BASE

SUBSTRATE -> METABOLIC ENZYME


					U3H27498KS

LAMOTRIGINE

SUBSTRATE -> METABOLIC ENZYME


					G819A456D0

ABIRATERONE

SUBSTRATE -> METABOLIC ENZYME


					MZ4L647O2H

N-Desmethylclobazam

INHIBITOR -> METABOLIC ENZYME

Interaction Type:

WEAK

Qualification:

IC50

Amount:


					3T1SS4E7AG

ENASIDENIB

SUBSTRATE -> METABOLIC ENZYME


					5YL4IQ1078

OSILODROSTAT

SUBSTRATE -> METABOLIC ENZYME


					G70A8514T8

FALECALCITRIOL

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MINOR


					U1JK633AYI

MOTESANIB

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MAJOR


					L5ORF0AN1I

ENTRECTINIB

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MINOR

Amount:


					Z5MR2Y1IJJ

ENAVOGLIFLOZIN

SUBSTRATE -> METABOLIC ENZYME

Amount:


					N62TGJ04A1

ESAXERENONE

SUBSTRATE -> METABOLIC ENZYME

Amount:


					XJR8Y07LJO

IMIDAFENACIN

SUBSTRATE -> METABOLIC ENZYME

Amount:


					N7U69T4SZR

OLANZAPINE

SUBSTRATE -> METABOLIC ENZYME


					69O5WQQ5TI

CYCLOBENZAPRINE

SUBSTRATE -> METABOLIC ENZYME


					6783M2LV5X

PEXIDARTINIB

INHIBITOR -> METABOLIC ENZYME

Qualification:

IC50

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED)	CHEMICAL