CAVROTOLIMOD

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Wed Apr 02 03:53:11 GMT 2025` Edited by `admin` on `Wed Apr 02 03:53:11 GMT 2025`
Nucleic Acid Type	OLIGONUCLEOTIDE
Sequence Type	COMPLETE
Record UNII	2Z5JOV1PPN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CAVROTOLIMOD

Official Name

English

DNA, D(P-THIO)(T-C-G-T-C-G-T-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T), 3'-(58-((3.BETA.)-CHOLEST-5-EN-3-YLOXY)-19,39,42-TRIHYDROXY-19,39-DIOXIDO-58-OXO-3,6,9,12,15,18,20,23,26,29,32,35,38,40,44,47,50,53-OCTADECAOXA-57-AZA-19,39-DIPHOSPHAOCTAPENTACONT-1-YL HYDR

Preferred Name

English

AST-008 OLIGONUCLEOTIDE

Code

English

AST-008

Code

English

cavrotolimod [INN]

Common Name

English

Cavrotolimod [WHO-DD]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

677419

Created by admin on Wed Apr 02 03:53:11 GMT 2025 , Edited by admin on Wed Apr 02 03:53:11 GMT 2025

Code System Code Type Description

FDA UNII

2Z5JOV1PPN

Created by admin on Wed Apr 02 03:53:11 GMT 2025 , Edited by admin on Wed Apr 02 03:53:11 GMT 2025

PRIMARY

SMS_ID

300000032233

Created by admin on Wed Apr 02 03:53:11 GMT 2025 , Edited by admin on Wed Apr 02 03:53:11 GMT 2025

PRIMARY

NCI_THESAURUS

C157771

Created by admin on Wed Apr 02 03:53:11 GMT 2025 , Edited by admin on Wed Apr 02 03:53:11 GMT 2025

PRIMARY

INN

11613

Created by admin on Wed Apr 02 03:53:11 GMT 2025 , Edited by admin on Wed Apr 02 03:53:11 GMT 2025

PRIMARY

INN

CAS

2378664-12-9

Created by admin on Wed Apr 02 03:53:11 GMT 2025 , Edited by admin on Wed Apr 02 03:53:11 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_1-1_24	24 / 24

Linkage	Site Range	Site Count
Phosporothioate	1_1-1_23	23 / 23

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CAVROTOLIMOD SODIUM

SALT/SOLVATE -> PARENT

Amount:

Related Record Type Details


					2Z5JOV1PPN

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOSIDE_SUBSTITUTION	[1_24]	3'-TERMINUS			UNSPECIFIED SUBSTANCE	d1a13d67 (not in database)