CYPROQUINATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H23NO5
Molecular Weight	357.4003
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)C1=CN=C2C=C(OCC3CC3)C(OCC4CC4)=CC2=C1O

InChI

InChIKey=JBCLGHRMQCEPFM-UHFFFAOYSA-N

InChI=1S/C20H23NO5/c1-2-24-20(23)15-9-21-16-8-18(26-11-13-5-6-13)17(7-14(16)19(15)22)25-10-12-3-4-12/h7-9,12-13H,2-6,10-11H2,1H3,(H,21,22)

HIDE SMILES / InChI

Molecular Formula	C20H23NO5
Molecular Weight	357.4003
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/18579783 | https://www.ncbi.nlm.nih.gov/pubmed/5458374

Cyproquinate is an anticoccidial drug, discovered by CIBA in the 1970s. Cyproquinate demonstrated marked anticoccidial activity against E. tenella infected chicks, and against a mixed coccidial infection. Cyproquinate also possessed antimalarial activity, as was demonstrated in a Novartis screen for antimalarial compounds.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Plasmodium falciparum 74 Target ID: CHEMBL364 Sources: https://www.ncbi.nlm.nih.gov/pubmed/18579783	Inhibitor 8297		5.72 nM [EC50]

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:02:23 GMT 2023` Edited by `admin` on `Fri Dec 15 15:02:23 GMT 2023`
Record UNII	2YTS3855OU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CYPROQUINATE

Official Name

English

CIPROQUINATE

Official Name

English

ciproquinate [INN]

Common Name

English

Ethyl 6,7-bis(cyclopropylmethoxy)-4-hydroxy-3-quinolinecarboxylate

Systematic Name

English

3-QUINOLINECARBOXYLIC ACID, 6,7-BIS(CYCLOPROPYLMETHOXY)-4-HYDROXY-, ETHYL ESTER

Common Name

English

NSC-142840

Code

English

SU-18137

Code

English

CYPROQUINATE [MI]

Common Name

English

CYPROQUINATE [USAN]

Common Name

English

Code System Code Type Description

CAS

19485-08-6