RETIFANLIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:18:09 UTC 2023` Edited by `admin` on `Sat Dec 16 14:18:09 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	2Y3T5IF01Z
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

RETIFANLIMAB

Official Name

English

AEX1188

Code

English

AEX-1188

Code

English

RETIFANLIMAB [USAN]

Common Name

English

retifanlimab [INN]

Common Name

English

INCMGA-00012

Code

English

MGA012

Code

English

MGA-012

Code

English

Retifanlimab [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PROGRAMMED CELL DEATH PROTEIN 1 (PROTEIN PD-1CD279 ANTIGEN))MONOCLONAL ANTIBODY.GAMMA.4 HEAVY CHAIN HUMANIZED (1-445) (VH (HOMO SAPIENS IGHV1-46*01 (82%) (IGHD)-IGHJ4*01 (93%)) (8.8.12) (1-119)-HOMO SAPIENS IGH

Common Name

English

ANTI-PD-1 MONOCLONAL ANTIBODY MGA012

Common Name

English

IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) (HUMANIZED MONOCLONAL MGA012 .GAMMA.4-CHAIN), DISULFIDE WITH HUMANIZED MONOCLONAL MGA012 .KAPPA.-CHAIN, DIMER

Common Name

English

INCMGA00012

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

691419

Created by admin on Sat Dec 16 14:18:10 UTC 2023 , Edited by admin on Sat Dec 16 14:18:10 UTC 2023

FDA ORPHAN DRUG

695719

Created by admin on Sat Dec 16 14:18:10 UTC 2023 , Edited by admin on Sat Dec 16 14:18:10 UTC 2023

Code System Code Type Description

DAILYMED

2Y3T5IF01Z

Created by admin on Sat Dec 16 14:18:10 UTC 2023 , Edited by admin on Sat Dec 16 14:18:10 UTC 2023

PRIMARY

CAS

2079108-44-2

Created by admin on Sat Dec 16 14:18:10 UTC 2023 , Edited by admin on Sat Dec 16 14:18:10 UTC 2023

PRIMARY

USAN

GH-96

Created by admin on Sat Dec 16 14:18:10 UTC 2023 , Edited by admin on Sat Dec 16 14:18:10 UTC 2023

PRIMARY

CAS

2226345-85-1

Created by admin on Sat Dec 16 14:18:10 UTC 2023 , Edited by admin on Sat Dec 16 14:18:10 UTC 2023

NO STRUCTURE GIVEN

FDA UNII

2Y3T5IF01Z

Created by admin on Sat Dec 16 14:18:10 UTC 2023 , Edited by admin on Sat Dec 16 14:18:10 UTC 2023

PRIMARY

INN

11095

Created by admin on Sat Dec 16 14:18:10 UTC 2023 , Edited by admin on Sat Dec 16 14:18:10 UTC 2023

PRIMARY

NCI_THESAURUS

C142168

Created by admin on Sat Dec 16 14:18:10 UTC 2023 , Edited by admin on Sat Dec 16 14:18:10 UTC 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_133	4_218
2_146	2_202
2_260	2_320
1_133	3_218
2_366	2_424
3_23	3_92
3_138	3_198
4_23	4_92
4_138	4_198
1_146	1_202
1_225	2_225
1_228	2_228
1_260	1_320
1_366	1_424

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_296
N	2_296

Related Record Type Details


					938DNF64FO

PROGRAMMED CELL DEATH PROTEIN 1

TARGET -> INHIBITOR

Retifanlimab-DLWR

SUB_CONCEPT->SUBSTANCE

Amount:

Related Record Type Details


					2Y3T5IF01Z

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL