U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:18:09 GMT 2023
Edited
by admin
on Sat Dec 16 14:18:09 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
2Y3T5IF01Z
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
RETIFANLIMAB
USAN   INN  
Official Name English
AEX1188
Code English
AEX-1188
Code English
RETIFANLIMAB [USAN]
Common Name English
retifanlimab [INN]
Common Name English
INCMGA-00012
Code English
MGA012
Code English
MGA-012
Code English
Retifanlimab [WHO-DD]
Common Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PROGRAMMED CELL DEATH PROTEIN 1 (PROTEIN PD-1CD279 ANTIGEN))MONOCLONAL ANTIBODY.GAMMA.4 HEAVY CHAIN HUMANIZED (1-445) (VH (HOMO SAPIENS IGHV1-46*01 (82%) (IGHD)-IGHJ4*01 (93%)) (8.8.12) (1-119)-HOMO SAPIENS IGH
Common Name English
ANTI-PD-1 MONOCLONAL ANTIBODY MGA012
Common Name English
IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) (HUMANIZED MONOCLONAL MGA012 .GAMMA.4-CHAIN), DISULFIDE WITH HUMANIZED MONOCLONAL MGA012 .KAPPA.-CHAIN, DIMER
Common Name English
INCMGA00012
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 691419
Created by admin on Sat Dec 16 14:18:10 GMT 2023 , Edited by admin on Sat Dec 16 14:18:10 GMT 2023
FDA ORPHAN DRUG 695719
Created by admin on Sat Dec 16 14:18:10 GMT 2023 , Edited by admin on Sat Dec 16 14:18:10 GMT 2023
Code System Code Type Description
DAILYMED
2Y3T5IF01Z
Created by admin on Sat Dec 16 14:18:10 GMT 2023 , Edited by admin on Sat Dec 16 14:18:10 GMT 2023
PRIMARY
CAS
2079108-44-2
Created by admin on Sat Dec 16 14:18:10 GMT 2023 , Edited by admin on Sat Dec 16 14:18:10 GMT 2023
PRIMARY
USAN
GH-96
Created by admin on Sat Dec 16 14:18:10 GMT 2023 , Edited by admin on Sat Dec 16 14:18:10 GMT 2023
PRIMARY
CAS
2226345-85-1
Created by admin on Sat Dec 16 14:18:10 GMT 2023 , Edited by admin on Sat Dec 16 14:18:10 GMT 2023
NO STRUCTURE GIVEN
FDA UNII
2Y3T5IF01Z
Created by admin on Sat Dec 16 14:18:10 GMT 2023 , Edited by admin on Sat Dec 16 14:18:10 GMT 2023
PRIMARY
INN
11095
Created by admin on Sat Dec 16 14:18:10 GMT 2023 , Edited by admin on Sat Dec 16 14:18:10 GMT 2023
PRIMARY
NCI_THESAURUS
C142168
Created by admin on Sat Dec 16 14:18:10 GMT 2023 , Edited by admin on Sat Dec 16 14:18:10 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
2_133 4_218
2_146 2_202
2_260 2_320
1_133 3_218
2_366 2_424
3_23 3_92
3_138 3_198
4_23 4_92
4_138 4_198
1_146 1_202
1_225 2_225
1_228 2_228
1_260 1_320
1_366 1_424
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_296
N 2_296
Related Record Type Details
TARGET -> INHIBITOR
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL