Details
Stereochemistry | ACHIRAL |
Molecular Formula | C15H22O4 |
Molecular Weight | 266.3328 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C(C)C(OCC=C(C)C)=CC(CO)=C1CO
InChI
InChIKey=DUMQPTRUYCCSEZ-UHFFFAOYSA-N
InChI=1S/C15H22O4/c1-10(2)5-6-19-14-7-12(8-16)13(9-17)15(18-4)11(14)3/h5,7,16-17H,6,8-9H2,1-4H3
Molecular Formula | C15H22O4 |
Molecular Weight | 266.3328 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/11853479Curator's Comment: The description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/12913305 | https://www.ncbi.nlm.nih.gov/pubmed/16593970 | https://www.ncbi.nlm.nih.gov/pubmed/28848500
Sources: https://www.ncbi.nlm.nih.gov/pubmed/11853479
Curator's Comment: The description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/12913305 | https://www.ncbi.nlm.nih.gov/pubmed/16593970 | https://www.ncbi.nlm.nih.gov/pubmed/28848500
Zinniol is a non-host selective phytotoxin which was originally isolated from culture filtrates of Alternaria zinnia, and then from those of A. dauci. This toxin induces several symptoms on zinnia and carrot and also inhibits seed germination of various plants. Zinniol has been shown to produce necrosis on leaves of susceptible marigold (Tagetes erecta) plants, probably through calcium regulation. The phytotoxin binds to carrot protoplasts and isolated membranes in a saturable and reversible manner. Receptor occupancy stimulates the entry of calcium into protoplasts. Zinniol can partially reverse the effects and binding of the calcium-channel blockers Desmethoxy-verapamil and bepridil. Selected cell lines that are insensitive to Zinniol lose part of their binding capacity and sensitivity to the action of the agonist-like compound but are still able to bind calcium-channel blockers.
Originator
Approval Year
Sample Use Guides
Certified seeds of T. erecta L. Were used for activity evaluation. Five-day-old cell cultures were transferred to liquid MS medium without growth regulators at a final density of 250,000 cells/ml and allowed to recover for 12 h (Wang et al. 1996). After this period, flasks were treated with different concentrations of the various phytotoxic fractions (Zinniol) and incubated at 25C for 48 h. Cell viability was determined with Evan’s blue
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 19:50:54 GMT 2023
by
admin
on
Fri Dec 15 19:50:54 GMT 2023
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Record UNII |
2XM821R13R
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Record Status |
Validated (UNII)
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Record Version |
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17811-28-8
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C051798
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2XM821R13R
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DTXSID10170425
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