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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H13FN2O4
Molecular Weight 243.2222
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALOVUDINE F-18

SMILES

CC1=CN([C@H]2C[C@H]([18F])[C@@H](CO)O2)C(=O)NC1=O

InChI

InChIKey=UXCAQJAQSWSNPQ-ZIVQXEJRSA-N
InChI=1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1/i11-1

HIDE SMILES / InChI

Molecular Formula C10H13FN2O4
Molecular Weight 243.2222
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

3'-[(18)F]fluoro-3'-deoxythymidine [[(18)F]-FLT or ALOVUDINE F-18], a tracer for positron emission tomography (PET) that is used for imaging of proliferation in human malignant lymphoma. This compound is also useful for making a proper diagnosis and monitoring treatment response of aplastic anemia patients, because can show overview of the bone marrow compartment in aplastic anemia.

Approval Year

PubMed

Substance Class Chemical
Record UNII
2X1K91UT6N
Record Status Validated (UNII)
Record Version