Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C10H13FN2O4 |
| Molecular Weight | 243.2222 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CN([C@H]2C[C@H]([18F])[C@@H](CO)O2)C(=O)NC1=O
InChI
InChIKey=UXCAQJAQSWSNPQ-ZIVQXEJRSA-N
InChI=1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1/i11-1
| Molecular Formula | C10H13FN2O4 |
| Molecular Weight | 243.2222 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
3'-[(18)F]fluoro-3'-deoxythymidine [[(18)F]-FLT or ALOVUDINE F-18], a tracer for positron emission tomography (PET) that is used for imaging of proliferation in human malignant lymphoma. This compound is also useful for making a proper diagnosis and monitoring treatment response of aplastic anemia patients, because can show overview of the bone marrow compartment in aplastic anemia.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| F-18 FLT PET: a noninvasive diagnostic tool for visualization of the bone marrow compartment in patients with aplastic anemia: a pilot study. | 2011 Apr |
|
| Imaging bone-marrow activity with (18)F-fluorothymidine PET. | 2018 Jan |
|
| Correlation between tumour biology status measured in triple-tracer 18F-fluorodeoxyglucose-18F-fluorothymidine- 18F-fluoromisonidazole-PET/CT study and human papillomavirus status in patients with head and neck cancer. | 2019 Jul |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:40:54 GMT 2023
by
admin
on
Fri Dec 15 15:40:54 GMT 2023
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| Record UNII |
2X1K91UT6N
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| Record Status |
Validated (UNII)
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| Record Version |
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C2124
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admin on Fri Dec 15 15:40:54 GMT 2023 , Edited by admin on Fri Dec 15 15:40:54 GMT 2023
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| Code System | Code | Type | Description | ||
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DB14930
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C002854
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C49093
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9878109
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100000127601
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2X1K91UT6N
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DTXSID90182869
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287114-80-1
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Fluorothymidine F-18
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SUB33646
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ACTIVE MOIETY |
