Amostomig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 20:39:53 GMT 2025` Edited by `admin` on `Wed Apr 02 20:39:53 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1\|LAMDA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	2WU34H9RT9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

H-gamma1 heavy chain anti-CD47 humanized (1-464) [VH(Homo sapiens IGHV3-23*04 (83.8%) -(IGHD) -IGHJ4*01(92.3%) L123>T (129), CDR-IMGT [8.10.20] (26-33.51-60.104-123)) (1-134)-Homo sapiens IGHG1*01v, G1m17,1>G1m3,1 CH1 R120, CH3 D12, L14, G1v14 CH2A1.3, A

Preferred Name

English

Amostomig

Official Name

English

amostomig [INN]

Common Name

English

Immunoglobulin G1-lambda, anti-[Homo sapiens CD47 (CD47 molecule, integrin associated protein, IAP, MER6, OA3)] and anti-[Homo sapiens CD274 (programmed cell death 1 ligand 1, PDL1, PD-L1, B7 homolog 1, B7H1, B7-H1, PDCD1LG1)], humanized monoclonal antib

Common Name

English

Immunoglobulin G1 [251-alanine,252-alanine], bispecific, anti-(human CD47 antigen) (human-Lama glama monoclonal BCD-106 ?1-chain), disulfide with human-Lama glama monoclonal BCD-106 ?-chain (243?232?),(246?235?),(371?355?)-tris(disulfide) with immunoglob

Common Name

English

Code System Code Type Description

CAS

2889449-09-4