Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C5H4N2O2 |
| Molecular Weight | 124.0975 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1=NC=CN=C1
InChI
InChIKey=NIPZZXUFJPQHNH-UHFFFAOYSA-N
InChI=1S/C5H4N2O2/c8-5(9)4-3-6-1-2-7-4/h1-3H,(H,8,9)
| Molecular Formula | C5H4N2O2 |
| Molecular Weight | 124.0975 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Identification and functional characterization of uric acid transporter Urat1 (Slc22a12) in rats. | 2011-06 |
|
| Synthesis, structure and magnetic properties of two new azido-Co(II) coordination architectures: from ferromagnetic coupling to single-chain-magnets. | 2010-12-14 |
|
| Poly[di-μ-aqua-μ(4)-(pyrazine-2,5-dicarboxyl-ato)-dilithium(I)]. | 2010-12-08 |
|
| Antimicrobial Susceptibility Testing of Mycobacterium bovis Isolates from Michigan White-Tailed Deer during the 2009 Hunting Season. | 2010-12-02 |
|
| Kinetics and inhibition of nicotinamidase from Mycobacterium tuberculosis. | 2010-11-09 |
|
| Reductive degradation of pyrazine-2-carboxylate by a newly isolated Stenotrophomonas sp. HCU1. | 2010-09 |
|
| A series of transition metal-azido extended complexes with various anionic and neutral co-ligands: synthesis, structure and their distinct magnetic behavior. | 2010-08-28 |
|
| Surveillance of pyrazinamide susceptibility among multidrug-resistant Mycobacterium tuberculosis isolates from Siriraj Hospital, Thailand. | 2010-08-20 |
|
| Synthesis and anti-mycobacterial evaluation of some pyrazine-2-carboxylic acid hydrazide derivatives. | 2010-08 |
|
| Molecular epidemiological study of pyrazinamide-resistance in clinical isolates of mycobacterium tuberculosis from South India. | 2010-07-07 |
|
| Xanthine oxidase inhibition by allopurinol increases in vitro pyrazinamide-induced hepatotoxicity in HepG2 cells. | 2010-07 |
|
| The near future: improving the activity of rifamycins and pyrazinamide. | 2010-05 |
|
| Poly[aqua-(μ-pyrazine-2-carboxyl-ato-κN,O:O)(μ-pyrazine-2-carboxyl-ato-κN,O:O')lead(II)]. | 2010-04-17 |
|
| Photoluminescent lanthanide-organic bilayer networks with 2,3-pyrazinedicarboxylate and oxalate. | 2010-04-05 |
|
| Peruvian and globally reported amino acid substitutions on the Mycobacterium tuberculosis pyrazinamidase suggest a conserved pattern of mutations associated to pyrazinamide resistance. | 2010-03 |
|
| QSAR modeling of a set of pyrazinoate esters as antituberculosis prodrugs. | 2010-02 |
|
| Epidemiology of gout. | 2010 |
|
| Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7) in human. | 2010 |
|
| What lies behind serum urate concentration? Insights from genetic and genomic studies. | 2009-12-29 |
|
| Poly[bis-(μ(2)-pyrazine-2-carboxyl-ato)-κN,O:O';κN,O:O-cadmium(II)]. | 2009-12-24 |
|
| Poly[hexa-aqua-bis(μ(3)-terephthalato)(μ(2)-terephthalato)diytterbium(III)]. | 2009-12-09 |
|
| Ligand-based modification of the structures and optical properties of new silver(I)-rhenate(VII) oxide/organic hybrid solids. | 2009-12-07 |
|
| Mutations found in the pncA gene of Mycobacterium tuberculosis in clinical pyrazinamide-resistant isolates from a local region of China. | 2009-11-26 |
|
| A polymorph of diaqua-bis(pyrazine-2-carboxyl-ato-κN,O)copper(II). | 2009-11-04 |
|
| Substituted N-Phenylpyrazine-2-carboxamides: synthesis and antimycobacterial evaluation. | 2009-10-20 |
|
| Tetra-ethyl-ammonium tricarbonyl-chlorido-(pyrazine-2-carboxyl-ato-N,O)rhenate(I). | 2009-10-17 |
|
| Combined Mössbauer spectral and density functional theory determination of the magnetic easy-axis in two high-spin iron(II) 2-pyrazinecarboxylate complexes. | 2009-09-07 |
|
| Poly[diaqua-(μ(2)-oxalato-κO,O:O,O)(μ(2)-pyrazine-2-carboxyl-ato-κN,O:O,O')neodymium(III)]. | 2009-08-12 |
|
| Interpreting expression data with metabolic flux models: predicting Mycobacterium tuberculosis mycolic acid production. | 2009-08 |
|
| Derivatives of pyrazinecarboxylic acid: 1H, 13C and 15N NMR spectroscopic investigations. | 2009-07 |
|
| Lipophilic pyrazinoic acid amide and ester prodrugs stability, activation and activity against M. tuberculosis. | 2009-06-28 |
|
| Protective effects of coffee-derived compounds on lipopolysaccharide/D-galactosamine induced acute liver injury in rats. | 2009-04 |
|
| The identification of orally bioavailable thrombopoietin agonists. | 2009-03-01 |
|
| Genome-wide analysis of the PreA/PreB (QseB/QseC) regulon of Salmonella enterica serovar Typhimurium. | 2009-02-23 |
|
| Metal and mixed-metal coordination polymers synthesized with pyrazine-2-carboxylate. | 2008-11-21 |
|
| Vibrational spectroscopic studies and ab initio calculations of a substituted amide of pyrazine-2-carboxylic acid--C12H10ClN3O. | 2008-11-15 |
|
| Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans. | 2008-10-03 |
|
| Poly[diaqua(μ(2)-oxalato-κO,O:O,O)(μ(2)-pyrazine-2-carboxyl-ato-κN,O:O')cerium(III)]. | 2008-09-20 |
|
| Synthesis and structures of a new series of silver-vanadate hybrid solids and their optical and photocatalytic properties. | 2008-09-15 |
|
| 4-Carboxy-pyridazin-1-ium chloride. | 2008-07-19 |
|
| Silymarin protects liver against toxic effects of anti-tuberculosis drugs in experimental animals. | 2008-07-05 |
|
| Medical management of genitourinary tuberculosis. | 2008-07 |
|
| Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13). | 2008-06-13 |
|
| Mechanistic implications of the active species involved in the oxidation of hydrocarbons by iron complexes of pyrazine-2-carboxylic acid. | 2008-04-21 |
|
| Diaqua-bis(pyrazine-2-carboxyl-ato-κN,O)manganese(II) dihydrate. | 2008-03-14 |
|
| Suppression of blood lipid concentrations by volatile Maillard reaction products. | 2008-01-24 |
|
| Interpretation of the multiple vanadium-oxygen bonds in the central VO(eta2-O2)+ group. Synthesis, structure, supramolecular interactions and DFT studies for complexes with 2,2'-bipyridine, 1,10-phenanthroline, pyrazinato(1-) and pyrazinamide ligands. | 2008-01-07 |
|
| 2'-(3-Hydroxy-benzyl-idene)pyrazine-2-carbohydrazide monohydrate. | 2007-12-06 |
|
| Dibromidobis(pyrazine-2-carboxylic acid-κN)mercury(II) dihydrate. | 2007-12-06 |
|
| Pyrazinamide and pyrazinoic acid activity against tubercle bacilli in cultured human macrophages and in the BACTEC system. | 1990-07 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:56:00 GMT 2025
by
admin
on
Mon Mar 31 19:56:00 GMT 2025
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| Record UNII |
2WB23298SP
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| Record Status |
Validated (UNII)
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| Record Version |
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C005296
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m9340
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PYRAZINOIC ACID
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