TEFIDSOGENE CIVAPARVOVEC

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 15:06:49 GMT 2023` Edited by `admin` on `Sat Dec 16 15:06:49 GMT 2023`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family	Parvoviridae
Organism Genus	Dependovirus
Organism Species	adeno-associated virus
Author	NONE
Infraspecific Type	SUBSTRAIN
Infraspecific Name	rAAV Rep2-Cap6-promoter-less hIDS-SA/hF9/exon 2-ZFN/hALB) intron 1
Part	WHOLE
Record UNII	2V7PRS3ISP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TEFIDSOGENE CIVAPARVOVEC

Official Name

English

A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS EXONS 2-9 FROM HIDS AND A SPLICE ACCEPTOR SITE (SA)

Systematic Name

English

SB-913

Common Name

English

tefidsogene civaparvovec [INN]

Common Name

English

Code System Code Type Description

INN

10981

Created by admin on Sat Dec 16 15:06:49 GMT 2023 , Edited by admin on Sat Dec 16 15:06:49 GMT 2023

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FDA UNII

2V7PRS3ISP

Created by admin on Sat Dec 16 15:06:49 GMT 2023 , Edited by admin on Sat Dec 16 15:06:49 GMT 2023

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NCI_THESAURUS

C171803

Created by admin on Sat Dec 16 15:06:49 GMT 2023 , Edited by admin on Sat Dec 16 15:06:49 GMT 2023

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CAS

2143580-10-1

Created by admin on Sat Dec 16 15:06:49 GMT 2023 , Edited by admin on Sat Dec 16 15:06:49 GMT 2023

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Related Record Type Details


					2V7PRS3ISP

TEFIDSOGENE CIVAPARVOVEC

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
TRANSGENE					TEFIDSOGENE CIVAPARVOVEC TRANSGENE INSERT	L7640Z83X9