MURAMYL DIPEPTIDE

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H32N4O11
Molecular Weight	492.4776
Optical Activity	UNSPECIFIED
Defined Stereocenters	7 / 7
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@H](NC(=O)[C@@H](C)O[C@@H]([C@H](O)[C@H](O)CO)[C@@H](NC(C)=O)C=O)C(=O)N[C@H](CCC(O)=O)C(N)=O

InChI

InChIKey=MEJOVVKHFORGKW-HOMBLFBHSA-N

InChI=1S/C19H32N4O11/c1-8(18(32)23-11(17(20)31)4-5-14(28)29)21-19(33)9(2)34-16(15(30)13(27)7-25)12(6-24)22-10(3)26/h6,8-9,11-13,15-16,25,27,30H,4-5,7H2,1-3H3,(H2,20,31)(H,21,33)(H,22,26)(H,23,32)(H,28,29)/t8-,9+,11+,12-,13+,15+,16+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C19H32N4O11
Molecular Weight	492.4776
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	7 / 7
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Dendritic cell maturation induced by muramyl dipeptide (MDP) derivatives: monoacylated MDP confers TLR2/TLR4 activation.	2005 Jun 1	15905553
Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release.	2007 Apr 15	17404311
The activation of gilthead seabream professional phagocytes by different PAMPs underlines the behavioural diversity of the main innate immune cells of bony fish.	2007 Mar	17087994
Cell culture models in developing nutrigenomics foods for inflammatory bowel disease.	2007 Sep 1	17568627
Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1).	2011 Feb	19897531

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:09:54 GMT 2023` Edited by `admin` on `Sat Dec 16 11:09:54 GMT 2023`
Record UNII	2U7S2HVO96
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MURAMYL DIPEPTIDE

Common Name

English

N-ACETYLMURAMYL-L-ALANINE-D-ISOGLN

Common Name

English

D-.ALPHA.-GLUTAMINE, N-(N-ACETYLMURAMOYL)-L-ALANYL-

Systematic Name

English

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE

Common Name

English

ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE

Common Name

English

N-(ACETYLMURAMYL)-L-ALANYL-D-ISOGLUTAMINE

Common Name

English

MURAMYL DIPEPTIDE [MI]

Common Name

English

D-.ALPHA.-GLUTAMINE, N2-(N-(N-ACETYLMURAMOYL)-L-ALANYL)-

Systematic Name

English

N2-(N-(N-ACETYLMURAMOYL)-L-ALANYL)-D-ALPHA-GLUTAMINE

Common Name

English

N-ACETYLMURAMYL DIPEPTIDE

Common Name

English

N-(ACETYLMURAMOYL)ALANYL-D-ISOGLUTAMINE

Common Name

English

MDP (Adjuvant)

Common Name

English

Code System Code Type Description

PUBCHEM

91667728