U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C7H12NO4S.Na
Molecular Weight 229.229
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM ACRYLOYLDIMETHYLTAURATE

SMILES

[Na+].CC(C)(CS([O-])(=O)=O)NC(=O)C=C

InChI

InChIKey=FWFUWXVFYKCSQA-UHFFFAOYSA-M
InChI=1S/C7H13NO4S.Na/c1-4-6(9)8-7(2,3)5-13(10,11)12;/h4H,1,5H2,2-3H3,(H,8,9)(H,10,11,12);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C7H12NO4S
Molecular Weight 206.239
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

2-Methyl-2-[(1-oxo-2-propenyl)amino]-1-propanesulfonic acid (AMPS) is an fda approved for use in polymer components of food-contact paper and board adhesive. Poly(2-acrylamido-2-methyl-1-propanesulfonic acid)(PAMPS)] has been found to inhibit the cytopathicity of HIV-1 and HIV-2 in MT-4 cells at concentrations that are not toxic to the host cells. It also inhibited syncytium formation in co-cultures of MOLT-4 cells with HIV-1- or HIV-2-infected HUT-78 cells. It inhibited binding of anti-gp120 mAb to HIV-1 gp120 and blocked adsorption of HIV-1 virions to MT-4 cells.

Approval Year

PubMed

PubMed

TitleDatePubMed
Anti-angiogenic activity of heparin-like polysulfonated polymeric drugs in 3D human cell culture.
2010-11
Use of amidoximated hydrogel for removal and recovery of U(VI) ion from water samples.
2010-10-15
Clinical effectiveness of contemporary dentin bonding agents.
2010-10
Enzymatic synthesis of semiconductor polymers by chloroperoxidase of Caldariomyces fumago.
2010-10
Electrochromatographic characterization of methacrylate ester-based monolith and capillary electrochromatography separation of flavonoids.
2010-09-15
Selective recognition of organic pollutants in aqueous solutions with composite imprinted membranes.
2010-09-15
Self-assembly of a series of random copolymers bearing amphiphilic side chains.
2010-09-15
Flower micelle of amphiphilic random copolymers in aqueous media.
2010-09-09
An intelligent multicompartmental system based on thermo-sensitive starch microspheres for temperature-controlled release of drugs.
2010-08
Spontaneous redifferentiation of dedifferentiated human articular chondrocytes on hydrogel surfaces.
2010-08
High yield sample preconcentration using a highly ion-conductive charge-selective polymer.
2010-07-15
Separation of peptides and oligonucleotides using a monolithic polymer layer and pressurized planar electrophoresis and electrochromatography.
2010-05-01
Hydrophobic-electrostatic balance driving the LCST offset aggregation-redissolution behavior of N-alkylacrylamide-based ionic terpolymers.
2010-04-20
Monolithic superhydrophobic polymer layer with photopatterned virtual channel for the separation of peptides using two-dimensional thin layer chromatography-desorption electrospray ionization mass spectrometry.
2010-03-15
Antimitogenic polymer drugs based on AMPS: monomer distribution-bioactivity relationship of water-soluble macromolecules.
2010-03-08
[Preparation of monolithic polylaurylmethacrylate column and its application in capillary electrochromatographic separation of myoglobin digests].
2010-03
Fabrication and characterisation of capillary polymeric monoliths incorporating continuous stationary phase gradients.
2010-03
Adamantyl-functionalized polymer monolith for capillary electrochromatography.
2010-02-26
In vitro differentiation of chondrogenic ATDC5 cells is enhanced by culturing on synthetic hydrogels with various charge densities.
2010-02
Hybrid polymer-silicon proton conducting membranes via a pore-filling surface-initiated polymerization approach.
2010-01
Design of self-oscillating gels and application to biomimetic actuators.
2010
[Synthesis and biological activity of complexes of sulfonate-containing polyanions and gentamycin].
2009-11-26
High binding capacity surface grafted monolithic columns for cation exchange chromatography of proteins and peptides.
2009-10-02
Preparation and evaluation of the highly cross-linked poly(1-hexadecane-co-trimethylolpropane trimethacrylate) monolithic column for capillary electrochromatography.
2009-10
Removal of toxic metal ions with magnetic hydrogels.
2009-09
Effect of temperature during photopolymerization of capillary monolithic columns.
2009-08
Rapid analysis of peptides and amino acids by CE-ESI-MS using chemically modified fused-silica capillaries.
2009-07
Using scanning contactless conductivity to optimise photografting procedures and capacity in the production of polymer ion-exchange monoliths.
2009-07
Complex nanoparticles based on chitosan and ionic/nonionic strong polyanions: formation, stability, and application.
2009-06
Dependence of protein recognition of temperature-sensitive imprinted hydrogels on preparation temperature.
2009-05-13
Alumina interaction with AMPS-MPEG copolymers produced by RAFT polymerization: stability and rheological behavior.
2009-05-01
Pore-functionalized polymer membranes for preconcentration of heavy metal ions.
2009-04-15
Synthesis of an imprinted hybrid organic-inorganic polymeric sol-gel matrix toward the specific binding and isotherm kinetics investigation of creatinine.
2009-03-15
PMMA-grafted nanoclay as novel filler for dental adhesives.
2009-03
CEC with new monolithic stationary phase based on a fluorinated monomer, trifluoroethyl methacrylate.
2009-02
Removal of As(V) from water by pectin based active hydrogels following geochemical approach.
2009-02
Design of a mass transport surface utilizing peristaltic motion of a self-oscillating gel.
2009-01-06
Preparation of organically functionalized silica gel as adsorbent for copper ion adsorption.
2009
Novel polymer blends for the preparation of membranes for biohybrid liver systems.
2009
Divalent cation-induced variations in polyelectrolyte conformation and controlling calcite morphologies: direct observation of the phase transition by atomic force microscopy.
2008-10-01
Optimization of serotonin imprinted polymers and recognition study from platelet rich plasma.
2008-09-15
Architecture of linear arrays of fluorinated co-oligomeric nanocomposite-encapsulated gold nanoparticles: a new approach to the development of gold nanoparticles possessing an extremely red-shifted absorption characteristic.
2008-09-02
A facile and simple method for the preparation of copoly(TEAMPS/VP)/silver nanocomposites for the humidity-sensing membranes.
2008-05-01
Spectroscopic investigations into degradation of polymer membranes for fuel cells applications.
2008-05
Removal of bovine serum albumin using solid-phase extraction with in-situ polymerized stationary phase in a microfluidic device.
2008-04-11
Ionic polymeric amphiphiles with cholesterol mesogen: adsorption and organization characteristics at the air/water interface from Langmuir film balance studies.
2008-04
Adsorption of 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) and related compounds onto montmorillonite clay.
2008-03-01
Evaluation of photografted charged sites within polymer monoliths in capillary columns using contactless conductivity detection.
2007-11
Preparation and evaluation of rigid porous polyacrylamide-based strong cation-exchange monolithic columns for capillary electrochromatography.
2007-11
Influence of Diamond Sono-Abrasion, Air-Abrasion and Er:YAG Laser Irradiation on Bonding of Different Adhesive Systems to Dentin.
2007-07
Patents
Substance Class Chemical
Created
by admin
on Wed Apr 02 18:11:45 GMT 2025
Edited
by admin
on Wed Apr 02 18:11:45 GMT 2025
Record UNII
2T9Q6EKI0G
Record Status Validated (UNII)
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Name Type Language
SODIUM AMPS
INCI  
Preferred Name English
SODIUM ACRYLOYLDIMETHYLTAURATE
Common Name English
2-ACRYLAMIDO-2-METHYLPROPANE-1-SULFONIC ACID SODIUM SALT
Common Name English
SODIUM 2-ACRYLAMIDO-2-METHYLPROPANESULFONATE
Systematic Name English
2-ACRYLAMIDO-2-METHYLPROPANESULFONIC ACID SODIUM SALT
Common Name English
ACRYLOYLDIMETHYLTAURINE SODIUM SALT
Common Name English
SODIUM ACRYLOYLDIMETHYL TAURATE
Common Name English
ACRYLOYLDIMETHYLTAURATE
Common Name English
SODIUM 2-ACRYLAMIDO-2-METHYL-1-PROPANESULFONATE
Systematic Name English
1-PROPANESULFONIC ACID, 2-METHYL-2-((1-OXO-2-PROPENYL)AMINO)-, MONOSODIUM SALT
Common Name English
1-PROPANESULFONIC ACID, 2-METHYL-2-((1-OXO-2-PROPEN-1-YL)AMINO)-, SODIUM SALT (1:1)
Common Name English
SODIUM N-ACRYLOYLDIMETHYLTAURATE
Common Name English
SODIUM 2-METHYL-2-((1-OXO-2-PROPENYL)AMINO)-1-PROPANESULFONATE
Systematic Name English
1-PROPANESULFONIC ACID, 2-ACRYLAMIDO-2-METHYL-, SODIUM SALT
Common Name English
SODIUM ACRYLAMIDOMETHYLPROPANESULFONATE
Systematic Name English
Classification Tree Code System Code
Food Contact Sustance Notif, (FCN No.) FCN NO. 148
Created by admin on Wed Apr 02 18:11:45 GMT 2025 , Edited by admin on Wed Apr 02 18:11:45 GMT 2025
Code System Code Type Description
PUBCHEM
23665719
Created by admin on Wed Apr 02 18:11:45 GMT 2025 , Edited by admin on Wed Apr 02 18:11:45 GMT 2025
PRIMARY
RXCUI
1370664
Created by admin on Wed Apr 02 18:11:45 GMT 2025 , Edited by admin on Wed Apr 02 18:11:45 GMT 2025
ALTERNATIVE
EPA CompTox
DTXSID2027591
Created by admin on Wed Apr 02 18:11:45 GMT 2025 , Edited by admin on Wed Apr 02 18:11:45 GMT 2025
PRIMARY
FDA UNII
2T9Q6EKI0G
Created by admin on Wed Apr 02 18:11:45 GMT 2025 , Edited by admin on Wed Apr 02 18:11:45 GMT 2025
PRIMARY
ECHA (EC/EINECS)
225-948-4
Created by admin on Wed Apr 02 18:11:45 GMT 2025 , Edited by admin on Wed Apr 02 18:11:45 GMT 2025
PRIMARY
CAS
5165-97-9
Created by admin on Wed Apr 02 18:11:45 GMT 2025 , Edited by admin on Wed Apr 02 18:11:45 GMT 2025
PRIMARY
DAILYMED
2T9Q6EKI0G
Created by admin on Wed Apr 02 18:11:45 GMT 2025 , Edited by admin on Wed Apr 02 18:11:45 GMT 2025
PRIMARY
RXCUI
1366964
Created by admin on Wed Apr 02 18:11:45 GMT 2025 , Edited by admin on Wed Apr 02 18:11:45 GMT 2025
PRIMARY RxNorm