NALOTIMAGENE CARMALEUCEL

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 15:40:28 GMT 2023` Edited by `admin` on `Sat Dec 16 15:40:28 GMT 2023`
Source Materials Class	ORGANISM
Source Materials Type	ALLOGENIC HUMAN
Source Materials Parent	`G0T704E6Z3` HOMO SAPIENS WHOLE
Part	BLOOD
Fraction Name	T CELLS
Record UNII	2SS05WO6EV
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NALOTIMAGENE CARMALEUCEL

Official Name

English

NALOTIMAGENE CARMALEUCEL [USAN]

Common Name

English

human culture expanded activated allogeneic T cells for adjunctive immunotherapy. Cells are derived from the haematopoietic stem cell (HSC) donor and are genetically modified ex vivo with a non-replicative SFCMM-3 gamma- retroviral vector derived from Mo

Common Name

English

HSV-TK

Code

English

nalotimagene carmaleucel [INN]

Common Name

English

Code System Code Type Description

INN

10786

Created by admin on Sat Dec 16 15:40:28 GMT 2023 , Edited by admin on Sat Dec 16 15:40:28 GMT 2023

PRIMARY

USAN

EF-65

Created by admin on Sat Dec 16 15:40:28 GMT 2023 , Edited by admin on Sat Dec 16 15:40:28 GMT 2023

PRIMARY

FDA UNII

2SS05WO6EV

Created by admin on Sat Dec 16 15:40:28 GMT 2023 , Edited by admin on Sat Dec 16 15:40:28 GMT 2023

PRIMARY

NCI_THESAURUS

C175827

Created by admin on Sat Dec 16 15:40:28 GMT 2023 , Edited by admin on Sat Dec 16 15:40:28 GMT 2023

PRIMARY

Related Record Type Details


					2SS05WO6EV

NALOTIMAGENE CARMALEUCEL

ACTIVE MOIETY

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
		RETROVIRAL TRANSFECTION		NALOTIMAGENE CARMALEUCEL VIRAL VECTOR	51G8GCR51J

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
GENE_EXPRESSION VECTOR					UNSPECIFIED SUBSTANCE	8650c76d (not in database)