Famzeretcel

Investigational

Approval Year

Substance Class	Structurally Diverse
Source Materials Class	ORGANISM
Source Materials Type	ALLOGENIC HUMAN
Source Materials State	LIVE
Source Materials Parent	`G0T704E6Z3` HOMO SAPIENS WHOLE
Part	embryo
Fraction Name	retinal progenitor cells (hrpcs) derived from foetal retina (17-20 weeks gestation)
Record UNII	2QX977G5YV
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

allogeneic human retinal progenitor cells (hRPCs) derived from foetal retina (17-20 weeks gestation). The retinal tissue undergoes dissection and digestion and the obtained cells are grown on fibronectin-coated plates under hypoxic conditions in serum fr

Preferred Name

English

Famzeretcel

Official Name

English

famzeretcel [INN]

Common Name

English

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Code System

Code

Type

Description

NCI_THESAURUS

C190367

PRIMARY

INN

12260

PRIMARY

SMS_ID

300000017412

PRIMARY

FDA UNII

2QX977G5YV

PRIMARY

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Related Record

Type

Details


					2QX977G5YV

Famzeretcel

ACTIVE MOIETY

Comments:

cell therapy (retinitis pigmentosa)

Amount:

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Agent Modifications

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Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
CULTURE	EXPANSION			FIBRONECTIN	WC7168JT17

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Name	Property Type	Amount	Referenced Substance
ANTIGEN EXPRESSED	BIOLOGICAL	[>95] % (limits)	`7K3K7A5WWS` Nestin

ANTIGEN EXPRESSED	BIOLOGICAL	[>85] % (limits)	`TD9WYF9YE9` Transcription factor SOX-2

ANTIGEN EXPRESSED	BIOLOGICAL	[<50] % (limits)	`VDH0F6EOX9` PROLIFERATION MARKER PROTEIN KI-67