Sutacimig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 17:55:09 GMT 2025` Edited by `admin` on `Wed Apr 02 17:55:09 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG4\|KAPPA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	2QP8468SQP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

H-gamma4 heavy chain anti-F7a humanized (1-448) [VH (Homo sapiens IGHV4-30-2*07 (92.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [9.7.15] (26-34.52-58.97-111)) (1-122)-Homo sapiens IGHG4*01 nG4m(a) CH2 L92, G4v5 h P10, G4v10 CH3 L85.1, K88 (CH1 (123-220), hing

Preferred Name

English

Sutacimig

Official Name

English

sutacimig [INN]

Common Name

English

Immunoglobulin G4 [230-proline,407-leucine,411-lysine,de-C-terminal-lysine], bispecific, anti-(human blood-coagulation factor VIIa) (human-Mus musculus monoclonal 11F2 ?4-chain), disulfide with human-Mus musculus monoclonal 11F2 ?-chain, (228?220?),(231?

Common Name

English

immunoglobulin (H-gamma4_L-kappa)_(H-gamma4_L-kappa), anti-[Homo sapiens F7 (coagulation factor 7, blood coagulation factor VII, coagulation serum prothrombin conversion accelerator) activated (F7a, F7A, FVIIa, FVIIA)] and anti-[Homo sapiens TREML1 (trig

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C211722

Created by admin on Wed Apr 02 17:55:09 GMT 2025 , Edited by admin on Wed Apr 02 17:55:09 GMT 2025

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CAS

2933972-64-4

Created by admin on Wed Apr 02 17:55:09 GMT 2025 , Edited by admin on Wed Apr 02 17:55:09 GMT 2025

PRIMARY

INN

13275

Created by admin on Wed Apr 02 17:55:09 GMT 2025 , Edited by admin on Wed Apr 02 17:55:09 GMT 2025

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FDA UNII

2QP8468SQP

Created by admin on Wed Apr 02 17:55:09 GMT 2025 , Edited by admin on Wed Apr 02 17:55:09 GMT 2025

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From	To
2_128	3_219
1_136	4_214
1_22	1_96
2_22	2_96
2_141	2_197
2_255	2_315
2_361	2_419
3_23	3_93
3_139	3_199
4_23	4_88
4_134	4_194
1_149	1_205
1_228	2_220
1_231	2_223
1_263	1_323
1_369	1_427

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_299
N	2_291

Related Record Type Details


					15FH07392N

COAGULATION FACTOR VIIA HUMAN

TARGET -> ACTIVATOR

Amount:

Related Record Type Details


					2QP8468SQP

Sutacimig

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1]	N-TERMINUS	Q	Amount:	PIDOLIC ACID	SZB83O1W42
AMINO_ACID_SUBSTITUTION	[2_1]	N-TERMINUS	Q	Amount:	PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL