AVOTERMIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Fri Dec 15 19:02:13 UTC 2023` Edited by `admin` on `Fri Dec 15 19:02:13 UTC 2023`
Protein Type	GROWTH FACTOR
Protein Sub Type	TGF .BETA. SUPERFAMILY
Sequence Type	COMPLETE
Record UNII	2Q1GS25JWN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AVOTERMIN

Official Name

English

HUMAN TGFB3

Common Name

English

HUMAN TRANSFORMING GROWTH FACTOR .BETA.-3

Common Name

English

Avotermin [WHO-DD]

Common Name

English

JUVISTA

Brand Name

English

avotermin [INN]

Common Name

English

HUMAN RECOMBINANT TRANSFORMING GROWTH FACTOR .BETA.-3

Common Name

English

HUMAN RECOMBINANT TRANSFORMING GROWTH FACTOR BETA 3 (E. COLI)

Common Name

English

AVOTERMIN [MART.]

Common Name

English

TRANSFORMING GROWTH FACTOR BETA-3 (RECOMBINANT)

Common Name

English

Code System Code Type Description

RXCUI

1427086

Created by admin on Fri Dec 15 19:02:13 UTC 2023 , Edited by admin on Fri Dec 15 19:02:13 UTC 2023

PRIMARY

RxNorm

INN

7628

Created by admin on Fri Dec 15 19:02:13 UTC 2023 , Edited by admin on Fri Dec 15 19:02:13 UTC 2023

PRIMARY

EVMPD

SUB05619MIG

Created by admin on Fri Dec 15 19:02:13 UTC 2023 , Edited by admin on Fri Dec 15 19:02:13 UTC 2023

PRIMARY

DAILYMED

2Q1GS25JWN

Created by admin on Fri Dec 15 19:02:13 UTC 2023 , Edited by admin on Fri Dec 15 19:02:13 UTC 2023

PRIMARY

FDA UNII

2Q1GS25JWN

Created by admin on Fri Dec 15 19:02:13 UTC 2023 , Edited by admin on Fri Dec 15 19:02:13 UTC 2023

PRIMARY

DRUG BANK

DB11955

Created by admin on Fri Dec 15 19:02:13 UTC 2023 , Edited by admin on Fri Dec 15 19:02:13 UTC 2023

PRIMARY

ChEMBL

CHEMBL2108833

Created by admin on Fri Dec 15 19:02:13 UTC 2023 , Edited by admin on Fri Dec 15 19:02:13 UTC 2023

PRIMARY

CAS

182212-66-4

Created by admin on Fri Dec 15 19:02:13 UTC 2023 , Edited by admin on Fri Dec 15 19:02:13 UTC 2023

PRIMARY

NCI_THESAURUS

C1847

Created by admin on Fri Dec 15 19:02:13 UTC 2023 , Edited by admin on Fri Dec 15 19:02:13 UTC 2023

PRIMARY

From	To
1_7	1_16
1_15	1_78
1_44	1_109
1_48	1_111
1_77	2_77
2_7	2_16
2_15	2_78
2_44	2_109
2_48	2_111

Related Record Type Details


					375142VBIA

INHIBITOR -> TARGET

Amount:


					2Q1GS25JWN

AVOTERMIN

INHIBITOR -> TARGET

Comments:

By mopping up active TGF beta, FmAb2 inhibits TGFβ signaling pathways

Amount:


					LZ88YF62H2

Ficerafusp Alfa

INHIBITOR -> TARGET

Amount:


					6EX05GL2VK

AVID-200

INHIBITOR -> TARGET

Qualification:

IC50

Amount:

Related Record Type Details


					2Q1GS25JWN

AVOTERMIN

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL