PHENYLGLYOXYLIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H6O3
Molecular Weight	150.1314
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)C(=O)C1=CC=CC=C1

InChI

InChIKey=FAQJJMHZNSSFSM-UHFFFAOYSA-N

InChI=1S/C8H6O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5H,(H,10,11)

HIDE SMILES / InChI

Molecular Formula	C8H6O3
Molecular Weight	150.1314
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
A health risk benchmark for the neurologic effects of styrene: comparison with NOAEL/LOAEL approach.	2001 Feb	11332541
Stereochemical metabolism of styrene in volunteers.	2001 Jul	11516070
GSTM1 polymorphism and styrene metabolism: insights from an acute accidental exposure.	2002 Aug 5	12191879
Relation between colour vision loss and occupational styrene exposure level.	2002 Dec	12468749
Interest of genotyping and phenotyping of drug-metabolizing enzymes for the interpretation of biological monitoring of exposure to styrene.	2002 Dec	12464798
Reactivity of intermediates in benzoylformate decarboxylase: avoiding the path to destruction.	2002 Dec 18	12475322
Analysis of styrene and its metabolites in blood and urine of workers exposed to both styrene and acetone.	2002 Jan-Feb	11888014
Simultaneous determination of styrene, toluene, and xylene metabolites in urine by gas chromatography/mass spectrometry.	2002 Oct	12373452
alpha-Keto amides as precursors to heterocycles--generation and cycloaddition reactions of piperazin-5-one nitrones.	2003 Apr 7	12926386
A transient intermediate in the reaction catalyzed by (S)-mandelate dehydrogenase from Pseudomonas putida.	2003 Nov 11	14596603
Esters of mandelic acid as substrates for (S)-mandelate dehydrogenase from Pseudomonas putida: implications for the reaction mechanism.	2004 Feb 24	14967029
A rapid HPLC method for the determination of carboxylic acids in human urine using a monolithic column.	2004 Jan	14598013
High resolution structures of an oxidized and reduced flavoprotein. The water switch in a soluble form of (S)-mandelate dehydrogenase.	2004 Jan 30	14604988
Evaluation of the efficiency of respiratory protective equipment based on the biological monitoring of styrene in fibreglass reinforced plastics industries.	2004 Mar	15090688
[Use of phenylglyoxylic ketyl radicals in testing for antioxidative effects of various compounds].	2004 May	15218736
A hybrid density functional study of O-O bond cleavage and phenyl ring hydroxylation for a biomimetic non-heme iron complex.	2004 May 17	15132638
Intermediates and transition states in thiamin diphosphate-dependent decarboxylases. A kinetic and NMR study on wild-type indolepyruvate decarboxylase and variants using indolepyruvate, benzoylformate, and pyruvate as substrates.	2005 Apr 26	15835904
Silymarin and its components scavenge phenylglyoxylic ketyl radicals.	2006 Dec	16956731
Cytogenetic biomarkers, urinary metabolites and metabolic gene polymorphisms in workers exposed to styrene.	2006 Feb	16424821
Styrene-oxide N-terminal valine haemoglobin adducts in reinforced plastic workers: possible influence of genetic polymorphism of drug-metabolising enzymes.	2007 Jul 31	17566625
[Hearing function and solvent exposure: study of a worker population exposed to styrene].	2007 Jul-Sep	18409685
Antifungal agent and other constituents from Cynanchum otophyllum.	2007 Mar	17365709
A new family of D-2-hydroxyacid dehydrogenases that comprises D-mandelate dehydrogenases and 2-ketopantoate reductases.	2008 Apr	18391442
Iron(II) complexes of sterically bulky alpha-ketocarboxylates. structural models for alpha-ketoacid-dependent nonheme iron halogenases.	2008 Feb 18	18217706
An integrated approach to biomonitoring exposure to styrene and styrene-(7,8)-oxide using a repeated measurements sampling design.	2008 Sep	18608187
[Influence of ethylbenzene on the levels of mandelic acid and phenylglyoxylic acid in urine, ultrastructure and the expressions of Mitochondrial apoptotic-related proteins in the rat nephridial tissues].	2009 Nov	20137408
Assessing variability and comparing short-term biomarkers of styrene exposure using a repeated measurements approach.	2010 Jan 15	20117324
Use of the CYP2E1 genotype and phenotype for the biological monitoring of occupational exposure to styrene.	2010 Jan 15	20117323
Involvement of mitochondria-mediated apoptosis in ethylbenzene-induced renal toxicity in rat.	2010 May	20156836

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:53:54 GMT 2023` Edited by `admin` on `Fri Dec 15 17:53:54 GMT 2023`
Record UNII	2PZL5A0W0M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PHENYLGLYOXYLIC ACID

Systematic Name

English

2-OXO-2-PHENYLETHANOIC ACID

Systematic Name

English

GLYCOPYRRONIUM BROMIDE IMPURITY B [EP IMPURITY]

Common Name

English

OXOPHENYLACETIC ACID

Systematic Name

English

BENZOYLFORMIC ACID

Systematic Name

English

NSC-28293

Code

English

PHENYLOXOACETIC ACID

Systematic Name

English

BENZENEACETIC ACID, .ALPHA.-OXO-

Common Name

English

.ALPHA.-OXOBENZENEACETIC ACID

Systematic Name

English

.ALPHA.-KETOPHENYLACETIC ACID

Systematic Name

English

GLYOXYLIC ACID, PHENYL-

Common Name

English

2-OXO-2-PHENYLACETIC ACID

Systematic Name

English

Code System Code Type Description

CHEBI

18280